Seasonal Science Jobs in Watertown, MA
Takeda Pharmaceutical
$68000 - $81600 YEAR
Boston, MA
Passion for learning and advancing structural biology capabilities and drug discovery pipelines, including proactive investigation of new techniques and capabilities, advanced software and hardware and innovative experimental approaches Ability to work collaboratively in a fast-paced, matrixed environment with a collaborative and proactive mindset, motivated by a desire to create therapeutic molecules for the benefit of patients in need worldwide. A sucessful candidate should have: PhD degree in Structural Biology, Biophysics, Biochemistry/Enzymology, Protein Chemistry or a related field with 3+ years industry experience in pharmaceutical or biotechnology structural biology role; MS with 8+ years or BS with 12+ years industry experience also considered.
Takeda Pharmaceutical
$68000 - $81600 YEAR
Boston, MA
The successful candidate will: Plan and execute gene-to-structure projects and generate target co-complex structures with small molecules and/or biologic proteins using in-house equipment and software and / or contract research organizations. Experience with both crystallography and cryo-EM methods for data collection and structure determination, biophysical techniques (SPR, ITC, DLS, etc), crystallization automation capabilities, membrane protein production and characterization and / or CRO management is highly desirable.
Takeda Pharmaceutical
$80000 - $96000 YEAR
Boston, MA
You will engage with key stakeholders including computational science and R&D teams (e.g., discovery biology, pre-clinical sciences, translational medicine and biomarker teams, clinical teams, quantitative sciences, therapeutic area units and engineering) as well as be an integral collaborator with internal cross-functional groups, CROs, and academic partners. Join Takeda as a Senior Scientist, Computational biologist, and become part of a global team that leverages cutting-edge computational biology and AI/ML techniques to rigorously identify and evaluate disease-target-biomarker relationships and utilize human genetics to derive novel insights for drug discovery, indication expansion, and biomarker development.
Takeda Pharmaceutical
$90000 - $108000 YEAR
Boston, MA
Receives high level instructions on all work, determines methods for new assignments, works closely with manager, may manage junior staff Determines methods for new assignments; perform literature search as needed to propose and develops innovative solutions. Develop AI/ML models, knowledge graphs and NLP pipelines; incorporate computational strategies with graph-neural networks, deep learning, multimodal fusion, transformer models, transfer learning, contrastive learning as appropriate.
Takeda Pharmaceutical
$115000 - $138000 YEAR
Boston, MA
Drive deep cross-functional collaboration with other computational science and R&D teams (e.g., discovery biology, screening and validation, pre-clinical sciences, translational medicine and biomarker teams, computational chemistry, quantitative sciences, therapeutic area units and engineering). This role is responsible for leading a global team that leverages cutting-edge computational biology and AI/ML techniques to rigorously identify and evaluate disease-target-biomarker relationships and utilize human genetics to derive novel insights for drug discovery, indication expansion, and safety assessments.
Takeda Pharmaceutical
$180000 - $216000 YEAR
Boston, MA
Design DNA constructs for protein expression of antibodies, single domains, multispecifics, enzymes, membrane proteins, etc. in transient expression constructs or for lentiviral transduction in stable cell line generation or chimeric antigen receptor expression. Expertise in different molecular biology databases at NCBI, Uniprot, etc., and multiple molecular biology software tools, such as Geneious Prime and Biologics, Genedata Biologics, Snapgene.
Takeda Pharmaceutical
$150000 - $180000 YEAR
Boston, MA
The ideal candidate will have demonstrated experience impacting drug discovery exemplified by delivering molecules to the clinic, leveraging cutting-edge physics-based modeling, AI/ML-driven approaches, and generative chemistry, collaborating effectively with biologists, structural biologist, pharmacologists, DMPK scientists as well as leading and mentoring computational chemistry teams. Provide crucial technical knowledge and input to project teams to drive decision-making in drug discovery projects by applying in-depth knowledge of structure-activity relationships (SAR), target biology, and predictive methods for assessing on- and off-target activity, physical properties, pharmacokinetics / pharmacodynamics (PK/PD), and synthetic feasibility.
Takeda Pharmaceutical
$92000 - $110000 YEAR
Boston, MA
As a Computational Chemistry Leader, you will work as part of a multi-disciplinary team of Medicinal Chemists, Computational Chemists, Data Scientist, Structural Biologists, Pharmacologists and Biologists to provide Computational expertise to advance drug discovery projects. Expertise in a variety of computational tools and methodologies including docking, virtual screening, molecular dynamics, free energy perturbation, homology modeling, quantum mechanics, pharmacophore elucidation, data mining, machine learning, cheminformatics, clustering, similarity & diversity analysis.
Takeda Pharmaceutical
$72000 - $86400 YEAR
Boston, MA
The successful candidate will: Plan and execute protein production campaigns for structural biology efforts of small molecule and/or biologic complexes with target proteins in collaboration with structural biologists and protein chemists utilizing in-house protein production capabilities and contract research organizations, including utilization of in-house equipment and database resources. The ideal candidate will possess a strong background in the field of Protein Chemistry and/or Structural Biology and will use this expertise to produce and characterize proteins for structure determination by x-ray crystallography and cryo-EM as well as potential use in biochemical and biophysical assays to advance Takeda’s drug discovery programs.
Takeda Pharmaceutical
$90000 - $108000 YEAR
Boston, MA
This role focuses on supporting clinical-stage portfolios, including exploring new indications for our late-stage assets, biomarker discovery, molecular differentiation and biomarker-driven early clinical studies targeting rare autoimmune and immune-mediated diseases, IBD, Celiac Disease, Liver fibrosis, Dermatological, and Rheumatological conditions. Leverage high-dimensional datasets, including multi-omics data from translational and clinical studies, to explore new indications for our late-stage assets, biomarker discovery, molecular differentiation, stratify patients, and support drug combination studies.
Segal
Boston, MA
Segal is a privately owned, leading North American employee benefit, human resources and investment management consulting firm with over 80 years of history providing trusted advice that improves lives. Consider an internship with Segal where you can work on actual client deliverables and interesting assignments while enhancing your technical and interpersonal skills as you network and consider a career at Segal.
Takeda Pharmaceutical
Boston, MA
Join Takeda as an Antibody Discovery- In Vitro, Director where you will be an excellent addition to our fast paced and exciting team of committed scientists, using your depth and breadth of knowledge in the field of antibody discovery, optimization and progression of programs forward through discovery towards IND. As part of the Biotherapeutic Engineering Team, you will report to the Senior Director and work with the Global Biologics organization as a leader who has accountability for the performance and results of a significant research function or activity that incorporates in vitro based discovery platforms yeast and phage.
Takeda Pharmaceutical
$80000 - $96000 YEAR
Boston, MA
The person filling this role will: Collaborate with Global Biologics (GB) scientists to design, develop, optimize, and implement new automation solutions for GB teams, focusing on the selection, production, screening, and characterization of therapeutics across various modalities. See Takeda Pharmaceutical Terms of Use at https://www.takeda.com/terms-of-use/ and Privacy Policy at https://www.takeda.com/privacy-notice/ and SonicJobs Privacy Policy at https://www.sonicjobs.com/us/privacy-policy and Terms of Use at https://www.sonicjobs.com/us/terms-conditions.
Takeda Pharmaceutical
$92000 - $110000 YEAR
Boston, MA
You will work with stakeholders within BST, PTS, and with partners across the business including Clinical Pharmacology, Clinical Operations, Procurement, R&D and IT Quality, and Clinical Data Solutions to support clinical bioanalytical and biomarker scientific operations and logistics with external vendors thereby helping create high quality clinical data. A working knowledge of various analytical methods including ligand binding assays, LC/MS, qPCR, flow cytometry and immunohistochemistry as well as a working knowledge of fit-for-purpose assay rigor (qualification, validation, etc) requirements needed to support clinical endpoints would be beneficial for success in role.
Takeda Pharmaceutical
$55000 - $66000 YEAR
Boston, MA
In collaboration with structural biology personnel, this person will participate in managing crystallization and cryoEM laboratories, including operation of crystallization robotics and software systems as well as ensuring laboratory safety compliance, consumable materials stocking and equipment maintenance are met. Strong computer skills including Microsoft Office applications required; experience with instrument control application software, LIMS systems (ie, sample inventory, data repositories), and/or electronic laboratory notebooks highly desirable.
Takeda Pharmaceutical
$150000 - $180000 YEAR
Boston, MA
Lead a team responsible for the design, development and execution of state-of-the-art in vitro pharmacology assays to evaluate the biological activity, potency, efficacy, and mechanism of action of our novel therapeutics, utilizing cutting-edge technologies (e.g., complex cell-based assays, co-culture systems, and 3D organoid models) to measure cellular responses in inflammatory pathways, and neuronal cell signaling. Strong technical proficiency in a wide range of in vitro pharmacology techniques and assay formats, including complex cell-based phenotypic assays, immune cell-based assays, co-culture systems, inflammation-based assays, neuronal models and GI organoid systems, flow cytometry, and high content imaging.
XPO
Boston, MA
Preferred qualifications: Master’s degree or PhD in Data Science, Statistics, Applied Mathematics, Engineering, Computer Science or related field Strong leadership and communication skills. What you’ll do on a typical day: Leverage Machine Learning, AI, statistical and/or optimization methods to solve various problems in Pricing, Sales, and Finance in order to optimize revenue for the company.
US Navy
Cambridge, MA
It is preferred that the degree focuses on areas of study such as: international relations, political science, government, engineering, physical science, natural science, computer science, or other academic fields related to intelligence. Intelligence Officers serve as a key part of the Information Dominance Corps as they: Supervise the collection, analysis and dissemination of critical information.