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Associate Scientist #26-17122

US Tech Solutions, Inc.

South San Francisco, CA

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JOB DETAILS
SKILLS
Academic Research, Analysis Skills, Antibodies, Assays, Automation, Biochemistry, Biology, Biotech and Pharmaceutical, Cell Cultures, Chromatographic Systems, Chromatography, Cloning, Communication Skills, Cross-Functional, DNA, Detail Oriented, Dialysis, Documentation, Experiment Design, High Performance Liquid Chromatography (HPLC), High School Diploma, Inventory Management, Laboratory, Laboratory Equipment, Laboratory Operations, Liquid Chromatography-Mass Spectrometry (LC-MS), Molecular Biology, Organizational Skills, Presentation/Verbal Skills, Problem Solving Skills, Production Support, Protein Purification, Quality Control, Record Keeping, Regulatory Compliance, Securities and Exchange Commission (SEC), Team Player, Writing Skills
LOCATION
South San Francisco, CA
POSTED
Today
Duration: 12 months contract
Shift: Standard working hours
 
Job Description:
  • Support the IPP (Induced Proximity Platform) Development group.
  • Individual will provide laboratory support for protein purification activities and associated experiments.
  • This is a 100% onsite laboratory role in South San Francisco.
  • The ideal candidate is a hands-on laboratory scientist with strong protein purification experience who enjoys bench work and can independently execute laboratory protocols with accuracy. They should be detail-oriented, organized, capable of documenting results thoroughly, and able to communicate findings clearly with the team.
  • This role is heavily focused on laboratory execution rather than experimental design, making prior hands-on purification experience significantly more important than broad research experience.
 
Required Technical Experience:
  • Hands-on protein purification experience (highest priority)
  • Strong laboratory bench skills with extensive wet-lab experience
  • Experience with one or more of:
  • ÄKTA
  • FPLC
  • HPLC
  • Comfortable working in a laboratory environment 100% of the time
  • Experience following laboratory protocols accurately
  • Strong documentation and recordkeeping skills
  • Able to communicate experimental results clearly
 
Position Summary:
The Associate Scientist will support protein and antibody production, purification, and analytical activities within the Discovery Protein Science department. This role will primarily support the Induced Proximity Platform by executing established protein production and characterization workflows. The individual will contribute to multiple protein production requests, maintain accurate experimental records, and collaborate with cross-functional scientists to deliver high-quality protein reagents in a fast-paced research environment.
 
Key Responsibilities:
  • Perform AKTA/FPLC-based purifications (Affinity, ion-exchange (IEX), hydrophobic interaction chromatography (HIC), size-exclusion chromatography (SEC) and other chromatography-based methods) with a focus on antibody-based molecules.
  • Perform biochemical and biophysical characterization of proteins and antibodies using analytical HPLC, SDS-PAGE, endotoxin testing and LC-MS.
  • Perform transient and stable mammalian cell expression of recombinant proteins and antibodies, as needed.
  • Maintain detailed laboratory documentation and experimental records.
  • Support inventory management, reagent preparation, and laboratory organization.
 
Qualifications:
  • Associate's or Bachelor's degree in Biology, Biochemistry, Biotechnology, Molecular Biology, or a related scientific discipline
  • Minimum of 2 years of hands-on laboratory experience in protein purification, protein analytics, or related biologics research in an academic or industry setting
  • Proficiency with AKTA/FPLC chromatography systems, HPLC and related laboratory equipment
  • Experience with protein characterization and analytical techniques
  • Ability to follow established protocols with strong attention to detail
  • Effective written and verbal communication skills
 
Preferred Qualifications:
  • Knowledge of antibody formats, isotypes and structures
  • Understanding of sterile technique and mammalian cell culture practices
  • Familiarity with automation such as KingFisher and Hamilton
  • Hands-on experience in DNA construct design and molecular cloning
  • Demonstrated ability to work effectively in a collaborative, cross-functional research environment
  • Demonstrated scientific analysis and problem-solving skills
 
 
Basic Qualifications:
  • Masters degree OR
  • Bachelors degree and 2 years of experience OR
  • Associate?s degree and 4 years of experience OR
  • High school diploma / GED and 6 years of experience
 
Must Have Skill Sets:     
  • Protein Purification and Analytical Techniques
Experience with protein purification workflows and chromatography methods
Proficient in AKTA/FPLC chromatography instrumentation such as affinity, IEX, HIC and SEC
Ability to perform buffer exchange and dialysis
Perform and interpret basic protein QC analyses
Spectrophotometry and colorimetric assays for protein concentration
HPLC-based purity assessment
SDS-PAGE gel electrophoresis and imaging
Endotoxin testing
LC-MS sample preparation and submission
  • Hands-on Laboratory Experience
Minimum 2 years of laboratory experience in a scientific setting
Strong proficiency in micropipetting, sample preparation, SDS-PAGE, buffer preparation, and operation of standard laboratory equipment
Experience with sterile technique and mammalian cell culture handling
  • Attention to Detail and Communication
Ability to follow established laboratory protocols accurately and consistently
Strong documentation, organizational, and data-recording skills
Effective written and verbal communication skills within a collaborative research environment
 
Day to Day Responsibilities:
  • Support protein production and purification requests for the Induced Proximity Platform to enable discovery-stage research
  • Perform protein purification using AKTA/FPLC chromatography systems, including affinity, IEX, HIC, and SEC
  • Conduct SDS-PAGE, spectrophotometry, HPLC, and other protein characterization assays
  • Perform buffer exchange and dialysis
  • Perform small-scale purification using KingFisher
  • Operate automated liquid handling systems to support panel-based bispecific purification workflows
  • Culture and maintain mammalian cell lines as needed
  • Prepare laboratory reagents, buffers, and samples according to established protocols
  • Accurately document experimental procedures, observations, and results in laboratory records and electronic systems
  • Monitor laboratory inventory, organize consumables, and support routine laboratory maintenance activities
  • Collaborate with scientists and cross-functional team members to support project timelines and research priorities
  • Follow safety guidelines, sterile techniques, and laboratory compliance standards in all daily activities
 
About US Tech Solutions:
US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit www.ustechsolutions.com.
 
US Tech Solutions is an Equal Opportunity Employer.  All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
 
AI Statement: By applying, you acknowledge that AI-assisted tools may be used during hiring.
 

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