Job Description:
The Associate Scientist I will be a member of the client CMC Biologics Cell Culture Development group, responsible for providing support for the development of Client biologics and bioprocess innovation projects, performing laboratory maintenance, and executing tasks to support departmental and project goals. The candidate should have experience with standard cell culture, biochemistry, and molecular biology techniques and is expected to clearly communicate scientific rationale, methodology and results in written and oral formats.
Responsibilities:
Follow established experimental protocols and assess results with supervision
Maintain a can-do attitude to complete innovative projects while being flexible in work priorities based on business needs
Perform routine tasks such as media/buffer preparation, thawing of cryopreserved cells, cell culture passaging, aseptic flask sampling, bioreactor sampling, and cell banking to support ongoing projects
Take routine analytical measurements for cell growth, culture gas-content, pH, osmolality, nutrient and metabolite measurements and HPLC analysis of antibody titers
Prepare bench top bioreactors and supporting equipment for sterile operation
Maintain instrumentation, consumables inventory and general cleanliness of a developmental lab to create a safe, effective and efficient scientific working environment
Display effective organization, verbal and written communication skills for effective explanation of experimental results, and adherence to good documentation practices
Weekend work to support bioreactor and other vessel sampling and feeding, as required
Qualifications:
BS in Biological Sciences or Chemical/Biochemical Engineering or related field with 0-3 years of experience
Experience with aseptic technique, preferably mammalian cell culture
Hands-on experience with analytical instrumentation (Vi-Cell, BGA, HPLC and Cedex Bio) and cell culture equipment (biosafety cabinet, incubators, and microscopes)
Experience with Microsoft Office (Word, Excel, PowerPoint)
Preferred:
Experience in bioreactor operation and cell culture media preparation
Experience in single use cell culture tools employed in bioprocess development, including but not limited to deep well plates, shake flasks, ambr250 bioreactors, or other stirred tank bioreactors
Experience with programming (VBA, Python, Javascript, C++)
Understand statistical analysis using software (JMP, SIMCA, Minitab, Design Expert, R) and statistical design of experiments (DOE)
Physical Demands:
Capable of pushing heavy containers on wheels
Must be comfortable with physical activities of constant standing, walking, and sitting with arm stretching into biosafety cabinets for cell culture work and occasionally lifting 25 lbs
EEO:
Mindlance is an Equal Opportunity Employer and does not discriminate in employment on the basis of Minority/Gender/Disability/Religion/LGBTQI/Age/Veterans.