Job Title: Bench Scientist - II
Job Location: Cambridge, MA
Job Duration: Up to 2 Years with Potential for Extension
Pay Rate: $40.42/hr on w2
Job Description:
The ideal candidate will be a hands-on laboratory scientist who enProducts bench-based research, thrives in a fast-paced environment, and demonstrates exceptional attention to detail. This role is well-suited for individuals who are eager to learn new technologies, contribute to innovative research programs, and Product broad exposure across multiple stages of the antibody discovery process.
Key Responsibilities
• Perform routine and advanced molecular biology laboratory techniques in support of antibody discovery projects.
• Conduct PCR, DNA/RNA isolation, restriction digestions, gel electrophoresis, bead-based purification, and related molecular biology workflows.
• Support next-generation sequencing (NGS) library preparation and sequencing activities.
• Execute experiments requiring precise pipetting and handling of small-volume samples.
• Follow established laboratory protocols and standard operating procedures with a high degree of accuracy and consistency.
• Generate high-quality experimental data and maintain thorough laboratory documentation.
• Troubleshoot laboratory processes and identify opportunities for workflow improvements.
• Collaborate closely with scientists across molecular biology, immunization, and antibody discovery functions.
• Contribute to technology development initiatives, including automation and process optimization efforts.
• Participate in cross-training opportunities across the broader research team.
Required Qualifications
• Bachelor's degree in Molecular Biology, Biochemistry, Biotechnology, Cell Biology, Biological Sciences, or a related discipline.
• Research experience Producted through industry, academic, or laboratory-based environments.
• Hands-on experience with core molecular biology techniques, including:
o PCR
o DNA/RNA isolation
o Gel electrophoresis
o Pipetting and sample preparation
o General laboratory procedures
• Strong organizational skills and exceptional attention to detail.
• Ability to follow protocols precisely while maintaining high-quality standards.
• Excellent communication and teamwork skills.
• Demonstrated eagerness to learn new techniques and technologies.
Preferred Qualifications
• Master's degree in a related scientific field.
• Experience with:
o Next-Generation Sequencing (NGS)
o Library preparation workflows
o Antibody discovery platforms
o Phage display or yeast display technologies
o Laboratory automation systems
o Hamilton, Biomek, or similar robotic liquid handling platforms
• Exposure to experimental design, process improvement, or laboratory innovation initiatives.
• Data analysis experience related to sequencing or molecular biology workflows.
Role Summary:
Biomedicine Design is seeking a laboratory scientist (contingent worker) to support therapeutic antibody discovery programs. This role focuses on executing essential molecular biology workflows that support B cell-based discovery campaigns, immune library generation, and sequence characterization.
Working in a collaborative laboratory environment, the successful candidate will execute established molecular biology protocols—such as nucleic acid isolation, PCR amplification, cloning, and sample purification—and assist in preparing samples for Next-Generation Sequencing (NGS) and automated workflows. This is an exciting opportunity for an early-career scientist to apply core molecular biology skills to biotherapeutic discovery while Producting hands-on exposure to cutting-edge sequencing and laboratory automation technologies.
Role Responsibilities:
- Molecular biology support: Execute established molecular biology workflows, including RNA/DNA isolation from cell samples, reverse transcription (RT), PCR amplification, and standard molecular cloning.
- Library preparation & sample processing: Assist with the generation and cleanup of immune libraries and amplicons using magnetic beads (e.g., SPRI), restriction digests, and gel purification.
- Sequencing & automation assistance: Support sample preparation and quality control (quantification, sizing) for Next-Generation Sequencing (NGS); assist with running routine protocols on automated liquid handlers.
- Laboratory documentation & operations: Maintain clear, accurate records of experimental procedures and results in electronic laboratory notebooks (ELN); support reagent inventory and daily bench readiness.
- Team collaboration: Prioritize tasks across active discovery timelines and communicate experimental progress and observations to project teammates.
Qualifications:
Education Level:
- Bachelor’s (B.S.) or Master’s (M.S.) degree in Molecular Biology, Biochemistry, Biotechnology, Biology, or a related life sciences discipline.
Years of Experience:
- 0 – 2+ years of hands-on laboratory experience in an academic, biotechnology, or pharmaceutical research setting.
Required Skills:
- Hands-on experience with standard molecular biology techniques (such as DNA/RNA extraction, PCR setup, and agarose gel electrophoresis).
- Familiarity with routine nucleic acid purification (e.g., column- or magnetic bead-based cleanups) and quantification methods (e.g., NanoDrop, Qubit).
- Working knowledge of standard molecular cloning principles (e.g., primer design, restriction digests, or Gibson assembly).
- Strong attention to detail, good organizational skills, and thorough record-keeping habits.
Nice-to-Have Skills (Preferred):
- Familiarity with or interest in laboratory automation and automated liquid handling platforms (e.g., Hamilton, Biomek, Opentrons).
- Familiarity with Next-Generation Sequencing (NGS) library preparation workflows and QC (e.g., TapeStation/Bioanalyzer).
- Experience with or interest in utilizing Python and/or AI tools for data analysis or automation scripting.
- Exposure to B cell workflows, immunology concepts, or antibody discovery methods.