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Bioinformatician II

Abbott
  • Madison, Wisconsin
    29 days ago

    Job Description

    Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 122,000 colleagues serve people in more than 160 countries.

         

    JOB DESCRIPTION:

    Position Overview
    The Bioinformatician II is a mid-level role responsible for supporting clinical reporting through the monitoring and review of variant calls and other pipeline outputs, investigation of quality control issues, and participation in assay validation and regulatory inspections. This role involves conducting case investigations, supporting CAP proficiency testing, and documenting variant-level changes. In addition, the role is responsible for monitoring existing bioinformatic NGS pipelines, data management and delivery to customers. This individual builds on foundational knowledge to handle a broader range of bioinformatics assignments, contributes to tool and pipeline development, and collaborates across teams to meet project objectives. The ideal candidate will have a strong background in managing and working with NGS data, experience working in a regulated environment, and the ability to mentor junior staff.
    This position is onsite at our Madison location, with a Tuesday to Saturday work schedule.
    Essential Duties
    Include, but are not limited to, the following:
    • Implement, test, maintain, and customize available bioinformatics resources and scientific software/data sources in multiple programming languages and platforms for research support.
    • Develop front ends for analysis tools, visualize and compile results, facilitate routine data processing, migration, organization, and management tasks, and build project-specific workflows that implement automated analysis steps.
    • Investigate, customize, and prototype new bioinformatics resources and scientific software for biomedical data processing. This requires skills in multiple programming languages, databases, computational methods, scientific computing, large-scale data analysis, and working with heterogeneous biomedical data from multiple sources.
    • Apply software engineering principles to create reusable, modular, tested, version-controlled, repository-based, professional-quality informatics, software, and database resources.
    • Design, prototype, and evaluate innovative computational algorithms, data analysis techniques, and statistical methods for biomedical data processing, interpretation, and knowledge discovery. Explore and recommend alternative data processing approaches as appropriate.
    • Follow scientific literature and manuscripts, investigate emerging biomedical data processing methods, technologies, trends, and paradigms relevant to biomedical informatics, and contribute to manuscripts, grants, research proposals, and research planning activities.
    • Attend, contribute to, and present at internal and external scientific meetings and conferences.
    • Manage multiple bioinformatics collaborations and projects, while mentoring junior staff.
    • Support strategic planning, organization, management, utilization, and optimization of current and future bioinformatics resources, skills, and capabilities.
    • Collaborate with principal investigators (PIs), researchers, and fellow bioinformaticians to align bioinformatics activities with organizational objectives and maximize competitive advantage in biomedical research.
    • Interact with other research divisions, computing infrastructure teams, and external academic and industry partners.
    • Demonstrate excellent communication skills and a strong desire to collaborate with researchers conducting cutting-edge biomedical research.
    • Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
    • Support and comply with the company’s Quality Management System policies and procedures. Maintain regular and reliable attendance. Ability to act with an inclusion mindset and model these behaviors for the organization. Ability to work designated schedule. Ability to work nights and/or weekends, as needed. Ability to work on a mobile device, tablet, or in front of a computer screen and/or perform typing for approximately 95% of a typical working day. Ability to travel 5% of working time away from work location, may include overnight/weekend travel.
    • Contributes to internal knowledge sharing, standard operating procedure (SOP) updates, and cross-training.
    Minimum Qualifications
    • Bachelor’s Degree/Master’s Degree in Bioinformatics/Computer Science/Bioengineering/Computational Biology or related field. 2 years of job related experience in academic/industrial applied research environment in biomedical data analysis.
    • Demonstrated ability to understand and implement computational algorithms, statistical analysis methods, custom data analysis software. Demonstrated proficiency in software development in multiple programming languages, such as Python/Java, and derivatives. Demonstrated proficiency in downloading/learning/applying software and database resources for custom analysis and building workflows.
    • Demonstrated proficiency with Linux/UNIX based systems and shell scripting. Demonstrated ability in analyzing gene expression, genotyping, sequencing, CGH, or in specific field needed by the duties, and various biomedical databases.
    • Demonstrated proficiency with scientific computing and data visualization tools, such as MATLAB/R, and understanding of basic statistics. Demonstrated proficiency in software engineering processes, such as version control, backup, documentation, testing, validation.
    • Demonstrated familiarity with large-scale data analysis and utilization of high-performance computing systems, parallel programming. Demonstrated proficiency with NGS workflow processes and languages (e.g., Cromwell/WDL, Snakemake).
    • Demonstrated proficiency with cloud computing (e.g. DNAnexus). Demonstrated ability to perform the essential duties of the position with or without accommodation. Authorization to work in the United States without sponsorship.
    Preferred Qualifications
    • Master’s Degree in Bioinformatics/Computer Science/Bioengineering/Computational Biology or related field. 2+ years in large scale NGS operations industry environments. Proficiency in Linux based systems, Python and AWS.
    • Experience working in a regulated environment under CLIA/CAP and/or FDA guidelines.

         

    The base pay for this position is

    $68,000.00 – $136,000.00

    In specific locations, the pay range may vary from the range posted.

         

    JOB FAMILY:

    Research and Discovery

         

    DIVISION:

    ONCO Cancer Diagnostics

            

    LOCATION:

    United States > Madison : 1 Exact Lane

         

    ADDITIONAL LOCATIONS:

         

    WORK SHIFT:

    Standard

         

    TRAVEL:

    Yes, 5 % of the Time

         

    MEDICAL SURVEILLANCE:

    No

         

    SIGNIFICANT WORK ACTIVITIES:

    Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day), Keyboard use (greater or equal to 50% of the workday)

         

    Abbott is an Equal Opportunity Employer of Minorities/Women/Individuals with Disabilities/Protected Veterans.

         

    EEO is the Law link - English: http://webstorage.abbott.com/common/External/EEO_English.pdf

         

    EEO is the Law link - Espanol: http://webstorage.abbott.com/common/External/EEO_Spanish.pdf

    Numbers & Facts

    LocationMadison, Wisconsin
    IndustryHealthcare Services
    Company Size10,000 employees or more
    Year Founded1910
    Websitehttp://www.abbott.com/

    About Company

    At Abbott, we are enthusiastic, energetic and committed to doing great work every day. Our employees are passionate about helping to translate science into lasting contributions to health care and the health of people worldwide. At the heart of our organization is our "Promise for Life"—a statement that embodies our company's commitment to employees, shareholders, local communities and the people who depend on our company and products to live healthier lives.

    Vital to our promise is the speed in which we act, respond and deliver. As Abbott employees, we are ready to meet change and challenges head-on. As a result, we are a company that adapts quickly, and through our passion for innovation we are able to continually create a pipeline of products that help improve the length and quality of life around the world.

    We are proud of our rich, more than 120-year history. We continue to be driven to advance leading-edge science and technologies, support diversity, focus on exceptional performance and earn the trust of those we serve.

    Skills

    • Algorithmsunmatched
    • Amazon Web Services (AWS)unmatched
    • Analysis Skillsunmatched
    • Analysis Softwareunmatched
    • Assaysunmatched
    • Bioengineeringunmatched
    • Bioinformaticsunmatched
    • Biologyunmatched
    • Biomedical Researchunmatched
    • Biomedical Softwareunmatched
    • Biomedicineunmatched
    • Clinical Supportunmatched
    • Cloud Computingunmatched
    • Communication Skillsunmatched
    • Computer Programmingunmatched
    • Computer Scienceunmatched
    • Computer Skillsunmatched
    • Computer Systemsunmatched
    • Conferencesunmatched
    • Data Analysisunmatched
    • Data Managementunmatched
    • Data Migrationunmatched
    • Data Processingunmatched
    • Data Visualization Toolsunmatched
    • Documentationunmatched
    • EEO Regulationsunmatched
    • English Lawunmatched
    • FDA (Food and Drug Administration)unmatched
    • Genotypingunmatched
    • Grant Writingunmatched
    • Healthcareunmatched
    • Industrial Researchunmatched
    • Informaticsunmatched
    • International Healthunmatched
    • Javaunmatched
    • Keyboardsunmatched
    • Linux Operating Systemunmatched
    • MATLABunmatched
    • Medical Diagnosisunmatched
    • Medical Equipmentunmatched
    • Medical Productsunmatched
    • Mentoringunmatched
    • Mobile Devicesunmatched
    • Next Generation Sequencing (NGS)unmatched
    • Organizational Skillsunmatched
    • Parallel Programmingunmatched
    • Programming Languagesunmatched
    • Prototypingunmatched
    • Python Programming/Scripting Languageunmatched
    • Quality Controlunmatched
    • Quality Managementunmatched
    • R Programming Languageunmatched
    • Regulationsunmatched
    • Research Grantsunmatched
    • Research Skillsunmatched
    • Sales Pipelineunmatched
    • Schedule Developmentunmatched
    • Science Softwareunmatched
    • Software Developmentunmatched
    • Software Engineeringunmatched
    • Source Code/Configuration Management (SCM)unmatched
    • Standard Operating Procedures (SOP)unmatched
    • Statistical Algorithmsunmatched
    • Statisticsunmatched
    • Strategic Planningunmatched
    • Surveillanceunmatched
    • Team Playerunmatched
    • Testingunmatched
    • Typingunmatched
    • Unix Operating Systemsunmatched
    • Unix Shell Programmingunmatched
    • User Interface Toolsunmatched
    • Validation Testingunmatched
    • Willing to Travelunmatched
    • Workflow Analysisunmatched

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