Bioinformatics Pipeline Test Engineer

Katalyst HealthCares & Life Sciences Inc
  • San Diego, CA
    2 days ago

    Job Description

    We are seeking a Bioinformatics Test Engineer to validate and ensure the quality of NGS data pipelines and bioinformatics workflows. The role requires a strong blend of bioinformatics knowledge, QA expertise, and automation skills.

    • Strong understanding of NGS workflows (FASTQ, BAM, VCF)
    • Experience in bioinformatics pipeline testing or QA
    • Proficiency in Python scripting
    • Hands-on with Git and CI/CD tools
    • Experience with cloud platforms (AWS/GCP/Azure) and data pipelines
    • Strong problem-solving and communication skills

    Preferred Skills:

    • Experience in biotech/life sciences domain
    • Familiarity with Nextflow, Snakemake, or similar workflows
    • Exposure to regulated environments (CLIA/FDA)
    • What We're Looking For
    • Strong testing mindset + hands-on engineering skills
    • Ability to debug pipelines and explain thought process clearly
    • Experience with real-world data workflows (not just academic projects)
    • Mentions NGS pipelines + testing together
    • Has Python + Git + CI/CD
    • Mentions variant calling / VCF validation
    • Worked on cloud or production pipelines
    • Reject or deprioritize if:
    • Only academic bioinformatics (no testing/QA)
    • Only statistics validation (no system testing)
    • No Python or automation
    • No infra experience (cloud / CI/CD / DB)
    • Only local scripts, no real pipelines
    • Bachelor's degree in Bioinformatics, Computer Science, Software Engineering, Biology, Biotechnology, Biomedical Engineering, Genetics, Molecular Biology, or a related scientific or engineering discipline.
    • Design and execute testing strategies for NGS pipelines (alignment, variant calling, annotation)
    • Perform data validation, regression testing, and discrepancy analysis
    • Develop automated test scripts (Python)
    • Translate requirements into test cases and validation criteria
    • Work with CI/CD pipelines and cloud-based workflows
    • Collaborate with cross-functional teams to ensure data accuracy and reliability

    Numbers & Facts

    LocationSan Diego, CA

    Skills

    • Amazon Web Services (AWS)unmatched
    • Analysis Skillsunmatched
    • Automationunmatched
    • Bioinformaticsunmatched
    • Biologyunmatched
    • Biomedical Engineeringunmatched
    • Biotech and Pharmaceuticalunmatched
    • Business Activity Monitoring (BAM)unmatched
    • Cloud Computingunmatched
    • Communication Skillsunmatched
    • Computer Scienceunmatched
    • Continuous Deployment/Deliveryunmatched
    • Continuous Integrationunmatched
    • Cross-Functionalunmatched
    • Data Managementunmatched
    • Data Qualityunmatched
    • Debugging Skillsunmatched
    • Engineeringunmatched
    • FDA (Food and Drug Administration)unmatched
    • GCP (Good Clinical Practices)unmatched
    • Geneticsunmatched
    • Gitunmatched
    • Microsoft Windows Azureunmatched
    • Molecular Biologyunmatched
    • Next Generation Sequencing (NGS)unmatched
    • Problem Solving Skillsunmatched
    • Python Programming/Scripting Languageunmatched
    • Quality Assuranceunmatched
    • Regression Testingunmatched
    • Requirements Managementunmatched
    • Scripting (Scripting Languages)unmatched
    • Software Engineeringunmatched
    • Statisticsunmatched
    • System Testunmatched
    • Test Automationunmatched
    • Test Caseunmatched
    • Test Designunmatched
    • Test Scriptsunmatched
    • Test Strategyunmatched
    • Testingunmatched
    • Validation Testingunmatched

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