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Bioinformatics Scientist - III (Senior)

Primary Talent Partners

Cambridge, MA

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JOB DETAILS
SALARY
$96–$106 Per Hour
SKILLS
Alliance/Partner Management, Amazon Simple Storage Service (S3), Amazon Web Services (AWS), Analysis Skills, Artificial Intelligence (AI), Bash Scripting, Best Practices, Bioinformatics, Biology, Biostatistics, Biotech and Pharmaceutical, CDMA Development Group, Cardiovascular Disease, Cloud Computing, Communication Skills, Computer Systems, Cross-Functional, Data Analysis, Data Science, Data Sets, Disease, Drug Development, Drug Discovery, Epidemiology, Establish Priorities, Genetic Diseases, Genetics, Genomics, Genotyping, Immunology, Interpersonal Skills, Medicine, Metabolic Disorders, Neuroscience, Programming Languages, Proteomics, Python Programming/Scripting Language, R Programming Language, Risk, Sales Pipeline, Scientific Research, Statistics, Team Player
LOCATION
Cambridge, MA
POSTED
2 days ago
Primary Talent Partners has a new contract opening for a Bioinformatics Scientist - III (Senior) to join our pharmaceutical client in Cambridge, MA. This is a 23-month contract to start with the potential for extensions. 

Pay:$96.00 - $106.00/hr; W2 contract, no PTO, no Benefits. ACA-compliant supplemental package available for enrollment. Candidates must be legally authorized to work in the United States and must be able to sit on Primary Talent Partners W2 without sponsorship.


Description:
The Complex Disease Genetics (CDG) group within Client’s Data, AI and Genome Sciences (DAGS) Department is seeking a motivated scientist to support our Cambridge-based research initiatives in complex disease genetics. We welcome applications from scientists with a graduate degree (PhD or equivalent) in statistical genetics, genetic epidemiology, computational biology, biostatistics, or a related quantitative field with hands-on experience analyzing human genetics and multi-omics data.

Client has invested in external partnerships and collaborative initiatives to accelerate innovation in drug discovery and development. The CDG group leverages large-scale data resources, such as FinnGen, the Alliance for Genomic Discovery, Our Future Health, UK Biobank Pharma Proteomics Project, Open Targets, and other public and proprietary datasets, to advance Client’s drug development pipeline through human genetics. The candidate will contribute to the analysis of these large-scale datasets to support target identification and validation and the implementation of precision medicine strategies across therapeutic areas.


In this exciting role, you will:
  • Perform statistical genetics analyses for target discovery and validation using human genetics and multi-omics data
  • Support the development, implementation, and maintenance of analytical pipelines for reproducible genetic and genomic data analysis
  • Conduct genetic association analyses using large-scale biobank data (e.g., UK Biobank, FinnGen, Our Future Health, Alliance for Genomic Discovery)
  • Integrate and analyze public and proprietary genetic association summary statistics and conduct meta-analyses
  • Perform post-GWAS analyses to help elucidate causal mechanisms and prioritize gene targets (e.g., fine mapping, colocalization, Mendelian Randomization, TWAS, polygenic risk prediction)
  • Assist in integrating genetic association findings with multi-omics data (e.g., RNA-seq, ATAC-seq, QTLs) to support target prioritization
  • Stay current with new methods in statistical genetics and participate in evaluating and implementing emerging analytical techniques
  • Collaborate with wet-lab biologists, disease area experts, and data scientists to support research and patient stratification strategies


Required Experience and Skills:
  • PhD (or equivalent) in statistical genetics, genetic epidemiology, population genetics, computational biology, bioinformatics, biostatistics, epidemiology, or a related quantitative discipline, with a minimum of 5 year of postdoctoral or equivalent research experience in complex disease genetics
  • Research experience in human genetics, genomics, or related analysis, including genome-wide association studies (GWAS) and/or multi-omics analysis
  • Familiarity with analytical pipelines and best practices for reproducibility and scalability in genetic data analysis
  • Proficiency in programming languages commonly used in statistical genetics (e.g., R, Python, etc.)
  • Experience working with large-scale datasets in could-based computing and high-performance computing environments
  • Strong communication and interpersonal skills, with the ability to work effectively in multidisciplinary teams


Preferred Experience and Skills:
  • Experience with molecular phenotypes, such as transcriptomics or proteomics
  • Interest or background in cardiovascular/metabolic diseases, immunology, neuroscience, or other complex diseases
  • Experience with AI/ML methodology and/or application to genetics and omics analysis.


Note:
  • Please add publication on the resume.
  • Onsite role at Cambridge, MA.
  • Manager would like to consider people with 5+ year post PhD experience. Please only submit these candidates. Anyone with less than 5+ year relevant experience with be rejected.
  • Looking for strong experience with multi-omics data analysis and integration (e.g., RNA-Seq, single-cell RNA-Seq, genotype, spatial transcriptomics, OLINK).
  • Proficiency in R, Python, and Bash, with the ability to establish best practices for reproducible data analyses.
  • Experience with high-performance computing (HPC) systems and AWS Cloud Computing (e.g., IAM, S3 buckets).
  • Most important, someone who can work oniste. No hybrid or remote.
  • We would like to have someone with at least five years of experience after PHD.
  • Our team specifically is required to be on site.
  • Looking for multi omics experience.
  • Looking for both bulk and single cell experience.
  • Some spatial transcriptomics would be nice.
  • So Olink, some proteomics experience and genotype data experience.
  • Candidate will be working on the External datasets.
  • Nonlocal is Ok as long as they are able to relocate at the own expense for the start date.


Key Skills:
  • Required expertise with multi-omics data analysis and integration (e.g., RNA-Seq, single-cell RNA-Seq.
  • Transcriptomics analysis.
  • Proficiency in R and Bash.
  • High-performance computing (HPC) systems and AWS Cloud Computing (e.g., IAM, S3 buckets).


Primary Talent Partners is an Equal Opportunity / Affirmative Action employer committed to diversity in the workplace. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, age, national origin, disability, protected veteran status, gender identity, or any other factor protected by applicable federal, state, or local laws.

If you are a person with a disability needing assistance with the application or at any point in the hiring process, please contact us at info@primarytalentpartners.com

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