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Biological Scientist IV - Pulmonary

University of Florida

Gainesville, FL

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JOB DETAILS
SALARY
$70,000–$92,200 Per Year
SKILLS
Alpha Testing, Analysis Skills, Assays, Big Data, Biological Software, Biology, COPD (Chronic Obstructive Pulmonary Disease), Cell Cultures, Critical Care, Data Analysis, Experiment Design, IRB/IEC (Institutional Review Board/Independent Ethics Committee), Identify Issues, Licensing, Patents, Performance Analysis, Product Development, Research Skills, Respiratory Therapy, Sleep Medicine, Testing
LOCATION
Gainesville, FL
POSTED
Today
The Division of Pulmonary, Critical Care & Sleep Medicine is accepting applications for a Biological Scientist IV. The position will reside within the Division’s Alpha-1 Antitrypsin Laboratory and will report directly to Dr. Karina Serban, the laboratory director and an experienced physician-scientist in the field of Alpha-1 deficiency and chronic obstructive pulmonary disease (COPD).
Classification Title:

Biological Scientist IV

Classification Minimum Requirements:

Bachelor’s degree in biology or a related field and thirteen years of experience or Master’s degree in biology or a related field with eleven year of experience. Doctoral degree in biology or related field with eight years of experience.

Job Description:

The Division of Pulmonary, Critical Care & Sleep Medicine is accepting applications for a Biological Scientist IV. The position will reside within the Division’s Alpha-1 Antitrypsin Laboratory and will report directly to Dr. Karina Serban, the laboratory director and an experienced physician-scientist in the field of Alpha-1 deficiency and chronic obstructive pulmonary disease (COPD).

Human and murine tissue processing and epithelial cell isolation and precision cut lung slices (PCLS)-related Experiments 

  • Develop novel approaches and analytical tools as required to harvest and maintain epithelial cells and PCLSs cultures derived from human explanted lungs and murine lungs.
  • Design and develop dose escalation studies involving alveolar organoids and PCLSs cultures in accordance with IRB and IBC protocols.
  • Collect, dissect, examine and interpret results of human and murine epithelial cells and tissue harvest.
  • Develop, organize and conduct immunofluorescence and FACS analysis and data interpretation.
  • Design and direct metabolism assays (Seahorse), to include oversight of technicians performing testing, review and interpretation of results.
  • Provide intellectual input as to troubleshooting strategies utilized in organoids and PCLS cultures.

Scholarly activities related to Alpha-1 Antitrypsin Deficiency and COPD research conducted in the lab

  • Analyze and interpret data, prepare graphs and figures for meetings and grant submissions.
  • Present data and manuscripts in weekly lab meeting and annually in divisional meetings.
  • Design and direct ELISA testing for Alpha-1 Antitrypsin Deficiency to include oversight of technicians performing the testing, review and interpret the results.
  • Participate in bio-product development to include initial designs, pilot experiments, and collaborating with the Office of Technology and Licensing for assurance of appropriate patents.
  • Create or modify web-based tools and test potentially new software to provide statistical and computational tools for big data interpretation.

Managerial Duties

  • Supervise other scientists and undergraduate students.
  • Coordinate experiments involving human tissue harvest to include procedures in collaboration with lung transplant team and other research groups on campus.
  • Interact and coordinate with off-campus collaborators samples shipments, common on-line meetings, and in-person visits.
  • Prepare a quarterly report on the performance of the scientists and students, under direct supervision.
Expected Salary:

$70,000 - $92,200; Commensurate with education and experience

Minimum Qualifications:

Bachelor’s degree in biology or a related field and thirteen years of experience or Master’s degree in biology or a related field with eleven year of experience. Doctoral degree in biology or related field with eight years of experience.

Preferred Qualifications:

Experience with human and murine tissue handling, 3D culture of PCLS and epithelial cells in organoids model are a must. This position will require independent thinking and the ability to serve as leader on complex projects to investigate new molecular signaling and physiological changes in murine models of Alpha-1 deficiency and COPD. The successful candidate will demonstrate expertise in a variety of the field’s concepts, allowing for development of novel practices and procedures as well as being able to work independently with minimal supervision.

Special Instructions to Applicants:

Application must be submitted by 11:55 p.m. (ET) of the posting end date.

Health Assessment Required:Yes

 

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University of Florida

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