Biologist: Single-Cell Sequencing Scientist

Location: Boston, MA 02210– 100% Onsite
Pay Rate: $48.00–$57.28/hour
Duration: 6-Month Contract with Potential Extension
Schedule: Monday–Friday, 8:00 AM–5:00 PM

Overview

The Biologist will join the Cardiometabolic Research team and support drug discovery and early-stage clinical research focused on diabetes, obesity, cardiovascular disease, and related metabolic disorders.

This position will primarily support next-generation sequencing initiatives, including RNA-seq, single-cell RNA-seq, single-nucleus RNA-seq, and other sequencing library preparation workflows. The role will collaborate across multiple research groups and therapeutic areas to support molecular biology, assay development, target identification, and data generation.

Required Qualifications

• Bachelor’s and/or Master’s degree in biological sciences, biochemical sciences, or a related field.

• 2 years of laboratory research experience.

• Strong hands-on molecular biology experience, including nucleic acid extraction and purification, quantification, NGS library preparation, quality control, and qPCR.

• Strong knowledge of next-generation sequencing technologies and applications, preferably including Illumina platforms.

• Direct experience with bulk RNA-seq and amplicon sequencing.

• Direct experience preparing single-cell RNA-seq and single-nucleus RNA-seq libraries.

• Experience with multiple scRNA-seq/snRNA-seq platforms, such as 10x Genomics Chromium, Illumina PIP-seq, ScaleBio, or Parse Biosciences.

• Strong organizational, time-management, documentation, and communication skills.

• Experience documenting laboratory activities in electronic laboratory notebook systems.

Preferred Qualifications

• Experience with CRISPR-based gene editing and high-throughput screening.

• Experience with laboratory automation systems, such as Mantis, Integra, liquid handlers, SPT Labtech Firefly, or Tecan.

Responsibilities

• Perform RNA-seq, scRNA-seq, snRNA-seq, and other next-generation sequencing library preparation workflows.

• Conduct molecular and cell biology experiments supporting drug discovery programs.

• Design and execute experiments to identify and validate potential drug targets.

• Support assay development, optimization, and validation.

• Perform nucleic acid extraction, purification, quantification, library preparation, and quality-control testing.

• Troubleshoot experimental workflows and analyze complex laboratory data.

• Support sequencing data generation and quality-control activities.

• Collaborate with cross-functional research teams across multiple therapeutic areas.

• Maintain accurate and detailed experimental documentation.

• Present experimental results, findings, and conclusions through written reports and verbal presentations.

Benefits

Employee contribution may apply.

• Health insurance

• Health savings account

• Dental insurance

• Vision insurance

• Flexible spending accounts

• Life insurance

• Retirement plan

All qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status. Rate of pay within the stated range will depend on the qualifications of the applicant.

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