Demeetra is seeking a highly motivated Cell Line Development Scientist to join our fast-paced team advancing next-generation gene editing technologies in bioproduction. This role is designed for someone who is eager, hands-on, detail-driven, and experienced enough to contribute with minimal onboard training. The successful candidate must be driven by a culture of excellence and ready for intense, high-expectation, hands-on CLD workflows, bringing industry experience that enables them to contribute at a high level from day one, ideally in a CRO or CDMO setting.
About the Role
You will be a key contributor in developing engineered CHO cell lines and optimizing upstream processes that support Demeetra’s cutting-edge gene editing platforms. This position is ideal for recent graduates (MS or PhD) and are eager to take ownership of experimental design, workflow execution, and timeline-driven deliverables.
Responsibilities
Execute CHO cell culture processes across shake flasks and spin tube fed-batch formats
Perform transfection, selection, single-cell cloning, and clone characterization workflows
Support upstream development with high attention to process consistency and data integrity
Vector design and molecular biology
Run titer and basic downstream quality assays to assess productivity and cell line performance, analytical experience (HPLC) is a plus.
Collaborate cross-functionally to implement advanced gene editing technologies in CLD
Contribute to workflow design, documentation, and continuous process improvement
Maintain a culture of excellence, accountability, and meeting or exceeding timelines
Required Qualifications
MS or PhD in biology, biochemistry, biotechnology, or related field required
Demonstrated proficiency in:
Molecular biology and vector construction
Suspension CHO cell culture
Transfection & selection workflows
Shake flask, spin tube, and deep-well plate fed-batch processes
Single-cell cloning
Titer determination and standard downstream quality assessments
Analytical techniques such as HPLC, LC/MS, and/or CE.
Ability to thrive in a high-expectation, fast-moving environment
Strong communication, organization, and documentation skills
Why Join Demeetra?
This is an opportunity to join a growing company at the forefront of gene editing applied to cell line development and bioprocessing. You will have significant hands-on impact, work with advanced technologies, and be part of an intensely collaborative and rewarding environment.
Industry
Biotechnology Research
Employment Type
Full-time
Numbers & Facts
Location
Lexington, Kentucky
Skills
Analysis Skillsunmatched
Assaysunmatched
Biochemistryunmatched
Biologyunmatched
Biotech and Pharmaceuticalunmatched
Cell Culturesunmatched
Cloningunmatched
Communication Skillsunmatched
Constructionunmatched
Contract Research Organization (CRO)unmatched
Cross-Functionalunmatched
Data Processingunmatched
Data Qualityunmatched
Documentationunmatched
Editingunmatched
Experiment Designunmatched
High Performance Liquid Chromatography (HPLC)unmatched