Cell Line Development Scientist

Demeetra Agbio Inc.
  • Lexington, Kentucky
    30+ days ago

    Job Description

    Demeetra is seeking a highly motivated Cell Line Development Scientist to join our fast-paced team advancing next-generation gene editing technologies in bioproduction. This role is designed for someone who is eager, hands-on, detail-driven, and experienced enough to contribute with minimal onboard training. The successful candidate must be driven by a culture of excellence and ready for intense, high-expectation, hands-on CLD workflows, bringing industry experience that enables them to contribute at a high level from day one, ideally in a CRO or CDMO setting.

    About the Role

    You will be a key contributor in developing engineered CHO cell lines and optimizing upstream processes that support Demeetra’s cutting-edge gene editing platforms. This position is ideal for recent graduates (MS or PhD) and are eager to take ownership of experimental design, workflow execution, and timeline-driven deliverables.

     

    Responsibilities

    • Execute CHO cell culture processes across shake flasks and spin tube fed-batch formats
    • Perform transfection, selection, single-cell cloning, and clone characterization workflows
    • Support upstream development with high attention to process consistency and data integrity
    • Vector design and molecular biology
    • Run titer and basic downstream quality assays to assess productivity and cell line performance, analytical experience (HPLC) is a plus.
    • Collaborate cross-functionally to implement advanced gene editing technologies in CLD
    • Contribute to workflow design, documentation, and continuous process improvement
    • Maintain a culture of excellence, accountability, and meeting or exceeding timelines

     

    Required Qualifications

    • MS or PhD in biology, biochemistry, biotechnology, or related field required
    • Demonstrated proficiency in:
      • Molecular biology and vector construction
      • Suspension CHO cell culture
      • Transfection & selection workflows
      • Shake flask, spin tube, and deep-well plate fed-batch processes
      • Single-cell cloning
      • Titer determination and standard downstream quality assessments
      • Analytical techniques such as HPLC, LC/MS, and/or CE.
    • Ability to thrive in a high-expectation, fast-moving environment
    • Strong communication, organization, and documentation skills

     

    Why Join Demeetra?

    This is an opportunity to join a growing company at the forefront of gene editing applied to cell line development and bioprocessing. You will have significant hands-on impact, work with advanced technologies, and be part of an intensely collaborative and rewarding environment.

     

    Industry

    • Biotechnology Research

    Employment Type

    • Full-time

    Numbers & Facts

    LocationLexington, Kentucky

    Skills

    • Analysis Skillsunmatched
    • Assaysunmatched
    • Biochemistryunmatched
    • Biologyunmatched
    • Biotech and Pharmaceuticalunmatched
    • Cell Culturesunmatched
    • Cloningunmatched
    • Communication Skillsunmatched
    • Constructionunmatched
    • Contract Research Organization (CRO)unmatched
    • Cross-Functionalunmatched
    • Data Processingunmatched
    • Data Qualityunmatched
    • Documentationunmatched
    • Editingunmatched
    • Experiment Designunmatched
    • High Performance Liquid Chromatography (HPLC)unmatched
    • Liquid Chromatography-Mass Spectrometry (LC-MS)unmatched
    • Microsoft Windows CE Operating Systemunmatched
    • Molecular Biologyunmatched
    • Organizational Skillsunmatched
    • Performance Analysisunmatched
    • Process Improvementunmatched
    • Team Playerunmatched
    • Time Managementunmatched

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