Analysis Skills, Assays, Biochemistry, Biology, Biotech and Pharmaceutical, Cell Cultures, Cloning, Communication Skills, Construction, Contract Research Organization (CRO), Cross-Functional, Data Processing, Data Quality, Documentation, Editing, Experiment Design, High Performance Liquid Chromatography (HPLC), Liquid Chromatography-Mass Spectrometry (LC-MS), Microsoft Windows CE Operating System, Molecular Biology, Organizational Skills, Performance Analysis, Process Improvement, Team Player, Time Management
Demeetra is seeking a highly motivated Cell Line Development Scientist to join our fast-paced team advancing next-generation gene editing technologies in bioproduction. This role is designed for someone who is eager, hands-on, detail-driven, and experienced enough to contribute with minimal onboard training. The successful candidate must be driven by a culture of excellence and ready for intense, high-expectation, hands-on CLD workflows, bringing industry experience that enables them to contribute at a high level from day one, ideally in a CRO or CDMO setting.
About the Role
You will be a key contributor in developing engineered CHO cell lines and optimizing upstream processes that support Demeetra’s cutting-edge gene editing platforms. This position is ideal for recent graduates (MS or PhD) and are eager to take ownership of experimental design, workflow execution, and timeline-driven deliverables.
Responsibilities
- Execute CHO cell culture processes across shake flasks and spin tube fed-batch formats
- Perform transfection, selection, single-cell cloning, and clone characterization workflows
- Support upstream development with high attention to process consistency and data integrity
- Vector design and molecular biology
- Run titer and basic downstream quality assays to assess productivity and cell line performance, analytical experience (HPLC) is a plus.
- Collaborate cross-functionally to implement advanced gene editing technologies in CLD
- Contribute to workflow design, documentation, and continuous process improvement
- Maintain a culture of excellence, accountability, and meeting or exceeding timelines
Required Qualifications
- MS or PhD in biology, biochemistry, biotechnology, or related field required
- Demonstrated proficiency in:
- Molecular biology and vector construction
- Suspension CHO cell culture
- Transfection & selection workflows
- Shake flask, spin tube, and deep-well plate fed-batch processes
- Single-cell cloning
- Titer determination and standard downstream quality assessments
- Analytical techniques such as HPLC, LC/MS, and/or CE.
- Ability to thrive in a high-expectation, fast-moving environment
- Strong communication, organization, and documentation skills
Why Join Demeetra?
This is an opportunity to join a growing company at the forefront of gene editing applied to cell line development and bioprocessing. You will have significant hands-on impact, work with advanced technologies, and be part of an intensely collaborative and rewarding environment.
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