Clinical Pharmacology Intern – Oncology

Job Title: Clinical Pharmacology Intern – Oncology
Location: San Diego, CA
Type: 12-week internship
Compensation: $28.62
Contractor Work Model: Hybrid or Remote
Hours: Monday–Friday, approximately 8–5

Overview
Leading pharmaceutical company looking for a Clinical Pharmacology Intern. Ideal candidates should be enrolled in a graduate level program

Must be a current PhD student (strong preference for 4th-5th year)

Responsibilities
• Support quantitative modeling analyses in early oncology drug development, focusing on applying advanced modeling approaches such as Tumor Growth Inhibition-Overall Survival (TGI-OS) and multistate models (MSMs).
• Conduct targeted literature reviews on quantitative modeling methods used to predict long-term efficacy endpoints like PFS and OS.
• Analyze early-phase clinical trial data using appropriate frameworks, implementing TGI-OS and/or MSM approaches to characterize tumor dynamics, disease transitions, and survival outcomes.
• Explore relationships between short-term efficacy endpoints (e.g., tumor size dynamics) and long-term clinical benefits.
• Interpret and synthesize modeling results within the context of oncology drug development and regulatory decision-making.
• Prepare a final presentation and written summary for internal scientific stakeholders.

Requirements
• Enrollment in a PhD program in pharmacometrics, clinical pharmacology, biostatistics, biomedical engineering, quantitative sciences, or related discipline (strong preference for 4th or 5th year).
• Strong quantitative and analytical background with a keen interest in oncology drug development.
• Practical experience with R for statistical or data analysis.
• Familiarity with longitudinal data analysis, survival analysis, or applied statistical modeling.
• Ability to clearly communicate scientific concepts, results, and interpretations in both written and verbal formats.

Preferred Qualifications
• Experience with pharmacometric or disease progression modeling (e.g., TGI, survival, multistate models).
• Familiarity with early-phase oncology clinical trial data and endpoints (e.g., ORR, tumor burden, PFS, OS).
• Interest in model-informed drug development (MIDD) and translational oncology research.
• Experience working with real-world data (RWD) or observational datasets.

Learning Outcomes
• Hands-on experience applying quantitative oncology modeling methods.
• Ability to interpret early efficacy data in relation to long-term outcomes.
• Competence in communicating results to multidisciplinary teams.

System One, and its subsidiaries including Joulé and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

Ref: #558-Scientific