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Clinical Research Associate III

Connexion Systems + Engineering

Durham, NC

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JOB DETAILS
SALARY
SKILLS
Biology, Cancer, Clinical Information Systems, Clinical Monitoring, Clinical Research, Clinical Support, Clinical Trial, Clinical Trial Management, Communication Skills, Compensation and Benefits, Contract Research Organization (CRO), Cross-Functional, Data Quality, Documentation, Electronic Data Capture (EDC), FDA Requirements, GCP (Good Clinical Practices), ICH Regulations, Informed Consent, Investigational New Drug (IND), Maintain Compliance, Nursing, Oncology, Operational Support, Organizational Skills, Patient Safety, Pharmacy, Phase I Clinical Trials, Problem Solving Skills, Product Management, RMON, Research Protocols, Site Evaluation, Standard Operating Procedures (SOP), Startup, Systems Engineering, Team Player, Willing to Travel
LOCATION
Durham, NC
POSTED
4 days ago
Connexion’s mission is to provide "best in class" services to job seekers. We strive to achieve excellence in job placement, staffing, and recruiting services, while treating candidates with the professionalism and respect they deserve.

Title: Clinical Research Associate III
Hiring Organization: Connexion Systems & Engineering

Compensation, Benefits, and Employment Type
  • Duration: 1+ year contract, possible extension
  • Pay rate: $50.02–$62.53/hour
  • Job Location: Durham, NC (travel required)
  • Schedule: Monday–Friday | 8:00 AM – 5:00 PM
  • Job#: bh19290

Description:
Our client is seeking an experienced Clinical Research Associate III to join its Clinical Operations team supporting Phase I oncology clinical trials. This is a sponsor-side role responsible for overseeing investigative sites, ensuring protocol compliance, protecting patient safety, and driving high-quality study execution.

This position is ideal for an experienced oncology CRA with direct early-phase (Phase I) monitoring experience who enjoys working collaboratively across cross-functional teams while serving as the primary sponsor representative for assigned study sites.

Responsibilities
  • Serve as the sponsor-side point of contact for assigned clinical trial sites.
  • Conduct site qualification, initiation, routine monitoring, and closeout visits.
  • Perform both onsite and remote monitoring in accordance with ICH-GCP, FDA regulations, study protocols, and sponsor SOPs.
  • Oversee informed consent, patient eligibility, treatment administration, safety reporting, investigational product management, protocol deviations, and data quality.
  • Evaluate site performance and proactively identify operational and quality risks.
  • Escalate issues affecting patient safety, data integrity, compliance, or study timelines.
  • Partner closely with Clinical Trial Managers, CROs, investigators, and cross-functional teams to resolve study issues.
  • Review monitoring documentation and ensure inspection-ready study conduct.
  • Support study startup activities, site activation, enrollment, and ongoing site engagement.
  • Maintain strong relationships with investigators, research coordinators, pharmacists, nurses, and site personnel.
  • Travel to investigative sites as needed.

Qualifications
Required:
  • Bachelor's degree in Life Sciences, Nursing, Pharmacy, or a related scientific field preferred.
  • Minimum 5 years of clinical monitoring experience.
  • Direct Phase I oncology monitoring experience is required.
  • Experience with dose-escalation studies and complex oncology protocols.
  • Strong knowledge of ICH-GCP guidelines and FDA regulations.
  • Experience using EDC, CTMS, eTMF, and other clinical trial systems.
  • Excellent communication, organizational, and critical thinking skills.
  • Ability to travel regularly for site monitoring.

Preferred:
  • Sponsor-side or sponsor-dedicated CRA experience.
  • Experience monitoring National Cancer Institute (NCI), cooperative group, or academic oncology studies.
  • Experience collaborating with CRO partners and multidisciplinary clinical teams.

If you're passionate about advancing innovative oncology therapies and thrive in a fast-paced clinical research environment, we'd love to hear from you. Apply today to learn more about this exciting contract opportunity.



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jobpostings@csetalent.com

. We would be glad to help you find the perfect job!

About the Company

C

Connexion Systems + Engineering

Connexion is an award-winning professional staffing firm that strives to be the unrivaled staffing solution for job seekers by expertly connecting talent with opportunity.  Over the last 20 years Connexion has built the most admired team of staffing experts in the industry.  We give back, change lives and offer unconditional support to the candidates we represent.

Put Connexion's 20 years of experience to work for you! Our professionals have unrivaled relationships and contacts with the hiring managers, human resources team and decision makers at the most desirable companies to work for.

Don't let your resume get lost in an inbox, Connexion's recruiting team will advocate on your behalf to get you the job you want

COMPANY SIZE
500 to 999 employees
INDUSTRY
Staffing/Employment Agencies
FOUNDED
1999
WEBSITE
https://www.csetalent.com/

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