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Mechanical Engineer Johns Hopkins Applied Physics Laboratory (APL)
Laurel, MD1 day ago
- $100,000–$245,000
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Skills
- Antibodiesunmatched
- Assay Developmentunmatched
- Assaysunmatched
- Biochemistryunmatched
- Biologyunmatched
- Biotech and Pharmaceuticalunmatched
- Communication Skillsunmatched
- Computational Engineeringunmatched
- Establish Prioritiesunmatched
- Experiment Designunmatched
- Functional Analysisunmatched
- Leadershipunmatched
- Molecular Biologyunmatched
- Patentsunmatched
- Publicationsunmatched
- Technical Leadershipunmatched
- Workflow Analysisunmatched
Description
We are recruiting for a research-driven biotechnology organization seeking a Computational Protein Engineer to lead hands-on antibody and protein engineering programs in Rockville, Maryland. This position combines wet-lab experimentation with computational design tools to accelerate discovery, guide design decisions, and improve experimental outcomes.
The organization offers scientists meaningful independence, access to accomplished colleagues, and the opportunity to pursue creative research with long-term impact.
Key Responsibilities
Lead antibody and protein engineering programs, including affinity maturation, multispecific antibodies, and novel binder development
Develop protein expression, purification, and analytical characterization workflows across multiple formats
Design binding, biochemical, and functional assays to evaluate engineered candidates
Apply tools such as AlphaFold, Rosetta, and ProteinMPNN to prioritize designs and guide laboratory strategies
Partner with structural biologists and computational scientists to translate modeling insights into experimental programs
Provide technical leadership across complex, multidisciplinary research initiatives
Communicate findings, recommendations, and project progress to scientific stakeholders
Qualifications
PhD in biochemistry, molecular biology, protein science, or a related discipline
Industry experience conducting hands-on antibody or protein engineering research
Strong expertise in protein expression, purification, characterization, and assay development
Experience with bispecific antibodies, nanobodies, multispecific proteins, or similar modalities
Familiarity with computational protein design and structure-prediction platforms
Scientific contributions demonstrated through publications, patents, or successful development programs
Ability to lead technical projects and collaborate across scientific disciplines
Apply today to explore a position where computational design and experimental protein engineering come together to advance meaningful scientific discovery.
Numbers & Facts
| Location | Rockville, MD |
| Industry | Staffing/Employment Agencies |
| Salary | $125,000–$165,000 |
| Company Size | 50 to 99 employees |
| Year Founded | 2002 |
| Website | https://www.gablessearch.com/ |
About Company
Gables Search Group headquartered in Cleveland, Ohio has been a leader in search and placement nationwide since 2002. Our company specializes in both direct and contract (temporary) staffing in all industries and disciplines.
At Gables Search Group, we connect exceptional professionals with outstanding organizations. Our commitment to integrity, excellence, partnership, innovation, and respect sets us apart. With a personalized approach to recruitment, we ensure the perfect match between candidates and employers.
Whether you are a talented professional seeking new opportunities or an organization looking to build a high-performing team, Gables Search Group is here to guide you through the journey. Our success is built on the success of our clients and candidates, and we are dedicated to making a positive impact on the careers and businesses we serve.