• Bellevue, NE
  • Quick Apply
16 days ago

Job Description

Responsibilities:
  • CQV resources supporting an NPD large-cap project modifying existing equipment and processes for future methods in an existing large-scale cell culture facility.
  • Focus on process equipment on the floor, walking systems down, and executing qualifications and related documentation.
  • All validation documentation and execution in ValGenesis (e-validation platform), including one documentation-focused resource.

Most Important Skills Needed:

  • Strong CQV experience with process equipment; able to work independently, set their own pace and goals, and still maintain team structure on second shift.
  • Hands-on execution of IQ and OQ and traditional qualification activities, including:
  • Walking drawings down and verifying against field configuration.
  • TOPs for materials certifications.
  • Verifying maintenance systems are active.
  • Verifying process flow paths and operation per functional design.
  • Wet testing.
  • SIP/CIP cycle development for flow paths in coordination with manufacturing engineering.
  • Post-IQ/OQ activities:
  • Steam-in-place temperature mapping.
  • BI (biological indicator) training and retrieval.
  • Pulling process data and working with QC lab reports.
  • Generating, executing, and reporting on validation documentation in ValGenesis.
  • Experience / comfort working with:
  • Large-scale cell culture (20kL bioreactor; batches 8 16kL).
  • Downstream equipment: harvest clarification, viral filtration, ultrafiltration, buffer transfer, tank farms, chromatography.
  • Steam clean-in-place activities.
  • Strong GDP and project timeline execution; ability to support compressed schedule with 2 3 shift coverage.
  • No CSV or lab validation required (process/CQV focus only).

Numbers & Facts

LocationBellevue, NE

Skills

  • CIP (Clean-in-Place)unmatched
  • Cell Culturesunmatched
  • Chromatographyunmatched
  • Data Processingunmatched
  • Documentationunmatched
  • Manufacturing Engineeringunmatched
  • Process Flowunmatched
  • Process Validationunmatched
  • Project Executionunmatched
  • Quality Controlunmatched
  • SIP (Sterilization-in-Place)unmatched
  • Technical/Engineering Designunmatched
  • Temperature Mappingunmatched
  • Validation Documentationunmatched

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