Join Immatics and shape the future of cancer immunotherapy; one patient at a time!
Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.
Why Join Us?
Innovative Environment: Help to pioneer advancements in cancer immunotherapy.
Collaborative Culture: Be part of a diverse team dedicated to your professional growth.
Global Impact: Contribute to therapies that make a lasting impact on patients globally.
Role Overview:
Immatics is seeking an experienced Director of Facilities, Engineering & Maintenance to lead the infrastructure and engineering operations that power our next-generation cell therapy manufacturing environments. This role is instrumental in ensuring our highly specialized GMP facilities can support clinical manufacturing, operational scalability, and future commercial readiness for innovative cancer immunotherapies. The ideal candidate combines deep technical expertise in regulated biopharmaceutical operations with strong leadership, operational excellence, and the ability to scale complex infrastructure in a high-growth environment.
Reports to: Chief Operating Officer
Location: 13203 Murphy Road, Suite 100, Stafford, TX 77477
Basic Qualifications:
Bachelor’s degree in Engineering (Mechanical, Electrical, Chemical, or related field)
10+ years of experience in facilities engineering and maintenance within biotech, pharmaceutical, or other GMP-regulated environments
5+ years of leadership experience managing engineering or facility operations teams
Demonstrated experience leading GMP facility projects (e.g., startup, expansion, or upgrades) and managing critical utilities and cleanroom operations
Proven experience ensuring compliance with GMP regulations, audits/inspections, and managing external contractors and capital projects
Preferred Qualifications:
Master’s degree in Engineering, Facilities Management, or a related discipline
Experience in commercial-stage cGMP manufacturing environments
Experience in cell therapy, biologics, or advanced therapy medicinal products (ATMPs)
Certification in Project Management (PMP), Facilities Management (CFM), or similar
Experience with advanced systems (e.g., BMS/EMS, MES, LIMS, ERP, automation, digital maintenance platforms)
Advanced expertise in reliability engineering, risk management, and large-scale infrastructure planning in regulated environments
Demonstrated ability to lead complex, cross-functional initiatives in high-growth settings
In this role you will:
Lead facility engineering and maintenance strategy to support GMP manufacturing, R&D operations, and company growth
Oversee operation, maintenance, and lifecycle management of critical systems (e.g., HVAC, cleanrooms, utilities, automation)
Ensure facility compliance with regulatory standards and maintain audit and inspection readiness
Drive capital planning, facility expansion projects, and infrastructure scaling for commercial manufacturing
Partner cross-functionally on deviations, CAPAs, change controls, and validation activities
Manage external vendors, contractors, and budgets to deliver projects on time and within scope
Build and lead a high-performing engineering team while driving continuous improvement, safety, and operational excellence
Travel required: up to 10% travel , domestically and internationally.
What do we offer?
At Immatics, we believe in investing in our team’s health, safety and well-being. Here’s what you can expect if you join Immatics
Comprehensive Benefits:
Competitive rates for Health, Dental, and Vision Insurance
4 weeks of vacation, granted up front each year and prorated for first and last year of employment.
12 company paid holidays
7 days of sick time
100% employer-paid life insurance up to at 1x annual salary, up to one hundred thousand dollars
100% employer-paid short- and long-Term disability coverage
401(k) with immediate eligibility and company match…
The company will match 100% of your contributions up to 3% of your base salary for the first two years of employment, 4% for years 2-3 of employment, and up to 5% of your salary from the fourth year onward of continued employment.
Partially paid parental leave for eligible employees.
Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.
Equal Employment Opportunity
We are an equal opportunity employer and are committed to building a diverse and inclusive workplace. We consider all qualified applicants for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, national origin, ancestry, age, marital status, disability, genetic information, veteran status, or any other status protected by applicable law.
Reasonable Accommodations
We are committed to providing reasonable accommodations to individuals with disabilities and to applicants with sincerely held religious beliefs, practices, or observances. If you require assistance or accommodation during the application or interview process, please contact us at PRIOR:
Work authorization/security clearance requirements
Legal eligibility to work in the United States is . Immatics participates in E-Verify and all new employees will be subject to the Department of Homeland Security requirements for employment
Affirmative Action/EEO statement
Immatics is an equal opportunity employer. All employment decisions including the decision to hire, promote, discipline, or discharge, will be based on merit, competence, performance, and business needs.
| Location | Houston, Texas |
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