We seek an experienced and creative medicinal chemist with a proven track record of success in drug discovery. Candidates should be motivated to work in an intensely collaborative, multidisciplinary, team -based setting. The role will entail coordinating a medicinal chemistry team with internal and external experimental capabilities, as well as proactively interfacing with diverse teams working on automated experimentation, AI -driven molecular generation, property predictions, and bioassay data generation.
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Lead a group of medicinal chemists and drive molecular discovery efforts to deliver development and clinical candidates
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Devise strategies to identify lead molecules and optimize them for potency, selectivity, and ADME properties using multivariant SAR analysis and hypothesis driven design principles
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Work closely with molecular and cellular biology, pharmacology, computational chemistry,
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ADME, and other key functions
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Act as liaison between Entos, CROs, and other external partners
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Influence the prospective use of computational methods and leverage automated synthesis
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and high -throughput experimentation capabilities
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Work closely with AI/ML teams to develop and implement relevant predictive models to aid
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in the design of new molecules
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Communicate project updates clearly and effectively to the broader team and key
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stakeholders
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Work as a senior member of the Chemistry research group and foster a culture of scientific
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excellence, innovation, and teamwork
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Ability to integrate multiple R&D disciplines into a successful strategic project plan
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Experience in leading projects and driving programs through the preclinical development
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process
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Experience working with computational chemists as part of project team in design of drug targets is required
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Strong interpersonal, communication, time management, and leadership skills
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Experience mentoring or leading junior chemists
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Creative problem solving and management of relationships with several stakeholders within
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and beyond the company
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Ability to integrate multiple R&D disciplines into a successful strategic project plan
<\/p><\/li>
Experience in leading projects and driving programs through the preclinical development
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process
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Experience working with computational chemists as part of project team in design of drug targets is required
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Strong interpersonal, communication, time management, and leadership skills
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Experience mentoring or leading junior chemists
<\/p><\/li>
Creative problem solving and management of relationships with several stakeholders within
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and beyond the company
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