Doctoral Research Faculty – Genomic Medicine Center

Doctoral Research Faculty – Genomic Medicine Center

Children’s Mercy Kansas City is recruiting a Doctoral Research Faculty for its’ Genomic Medicine Center.

The candidate will be responsible for maintaining a successful research program within the Genomic Medicine Center, Department of Pediatrics. The candidate will lead research projects that incorporate large-scale genome sequencing data from pediatric patients applying genomic approaches to rare and common pediatric disease and cancer. We are looking for excellent research scientists at early-stage and mid-career faculty levels. The candidates will have expertise in areas including bioinformatics, human genetics, molecular biology, medical genetics / genomics and share our passion for building a comprehensive translational research program intertwined with excellence in pediatric care. 

• Support the pharmacometrics and data analysis needs for clinical and basic research programs within the Division of Clinical Pharmacology and the Department of Pediatrics.
• Serve as an investigator, co-investigator, sub-investigator, or consultant on investigator-initiated grant proposals and sponsored contracts.
• Implementation of innovative, state-of-the-art methods in design optimization, modeling and simulation to improve clinical care, clinical research design, and data analysis.
• Training and educational materials in pharmacometrics principles and applications for students, postdoctoral trainees and faculty members
• Position requires a doctorate level degree

Among the first of its kind with a pediatric focus, the Genomic Medicine Center at Children's Mercy provides clinical genomic services and is an epicenter for genomic research. Although the Center focuses on sequencing and analyzing rare inherited diseases in children, expansion plans are underway to include translational cancer genomics and research on the use of pharmacogenomics in precision medicine.

Genomic Answers for Kids (GA4K) is changing the landscape of pediatric genomics through what may be the most advanced system for rare disease diagnosis in the world. The team has surpassed 1,000 rare diagnoses through their groundbreaking work—far out-pacing other rare disease research programs—and continue to conduct cutting-edge science that has led to a number of “firsts” in the field of genomics research.

GA4K has produced more than 1,000 genomes through a state-of-the-art technique called HiFi sequencing that allows them to see more of the human genome than other techniques; is the first to use 5-base sequencing in their genomic analyses, accelerating answers for kids with rare diseases through the sequencing of the full genome; and is the first to apply “human assembly” to their rare disease genomics work, building hundreds of genomes from scratch to capture the DNA that is missed by the human genome developed in 2014.

The Center's staff includes physicians, PhD-level scientists, nurses and clinical laboratory scientists experienced in genome analysis. The team features board-certified clinical molecular geneticists, genetic counselors, bioinformaticians and software engineers. The Center works closely with the Bioethics Center and collaborate with physicians representing every subspecialty at Children's Mercy.

Please apply online with a cover letter and your CV using the link below, or send to

physicianjobs@cmh.edu

The successful applicant must share our unwavering commitment to excellence, integrity, collegiality, antiracism, and respect for inclusion of individuals with diverse backgrounds.