Downstream Development Associate II

Lundbeck

Bothell, WA

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JOB DETAILS

SKILLS

Analysis Skills, Antibodies, Biochemistry, Biotech and Pharmaceutical, Centrifuge, Chemical Engineering, Chemistry, Communication Skills, Data Analysis, Drug Manufacturing, Drug Products, High Performance Liquid Chromatography (HPLC), Laboratory Equipment, Lift/Move 30 Pounds, Liquid Chromatography, Manufacturing/Industrial Processes, Neurology, Organizational Development/Management, Organizational Skills, Physical Chemistry, Presentation/Verbal Skills, Process Development, Process Validation, Product Development, Product Support, Psychiatry and Mental Health, Pumps, Sales Pipeline, Team Player, Unicorn Library Management System

LOCATION

Bothell, WA

POSTED

30+ days ago

Downstream Development Associate II Requisition ID: 7833 Location: Bothell, WA, US Do you want to join a team where the mission is meaningful, the challenges are complex, and you can directly see the results of your hard work? Lundbeck Seattle BioPharmaceuticals (Lu-SBP), located in Bothell, Washington, is the Process Development Center of Excellence for Biologics within the global Lundbeck CMC organization. Since integrating into Lundbeck in October 2019, Lu-SBP has supported commercial launch of Lundbeck's first biologic product (Vyepti) and advancement of a growing biologics pipeline in collaboration with our Copenhagen-based Process Science & Validation Team. The Lu-SBP team leads and supports the development of new product candidates from cell line development through commercial validation of Drug Substance and Drug Product manufacturing processes. Join us on our journey to advance brain health and transform lives. **Summary:** Performs downstream process development experiments and supporting activities, which enable both early and late-stage manufacturing process design for therapeutic monoclonal antibody production via yeast and mammalian expression systems. **Essential Functions:** + Performs small-scale downstream process development experiments for monoclonal antibodies, as applied to liquid chromatography and tangential/normal flow filtration. + Prepares experimental intermediate samples for further analytical testing, including purification via miniature liquid chromatography and ultrafiltration devices. + Prepares purified protein product to support upstream process development and supply further downstream process development activities. + Performs analytical methods, such as UV-visible spectrophotometry, turbidimetry, density measurement, size exclusion and protein A affinity HPLC, and biolayer interferometry. + Organizes and analyzes primary data and prepares concise presentations and reports. **Required Education, Experience, and Skills:** + Accredited bachelor's degree and a minimum of 2+ years of biotechnology/pharmaceutical industry experience or equivalent combination of education and experience totaling 4 years. + Basic understanding of the principles of liquid chromatography, membrane filtration, sedimentation/centrifugation, aqueous physical chemistry, and protein chemistry. + Familiar with basic laboratory equipment, including pH, conductivity, & temperature meters, pumps, pressure gauges, weight scales, pipette dispensers, and tabletop centrifuges. + Excellent verbal communication skills to interact collaboratively with Process Development teammates. + Well-developed organizational skills and the ability to take a proactive approach to job responsibilities. + Ability to comply with FDA GMP documentation regulations and industry standard safety practices. + Proficiency in Microsoft Windows 10/Office. + Must be able to lift to 30 pounds on occasion. **Preferred Qualifications, Skills and Competencies** + An accredited B.S. degree in science or engineering (i.e. Biochemical Engineering, Chemical Engineering, Biotechnology Engineering, Biochemistry, Biotechnology or equivalent). + Experience with analytical techniques such as HPLC, UPLC, and/or CE a plus. + Experience with pilot scale operations a plus. + Experience with MPLC systems such as the Äkta/Unicorn platform a plus. The range displayed is specifically for those potential hires who will work or reside in the state of Washington, if selected for this role, and may vary based on various factors such as the candidate's qualifications, skills, competencies and proficiency for the role. Salary Pay Range: $38/hour - $45/hour and eligibility for an 8% bonus target based on company and individual performance. Additional benefits for this position include flexible paid time off (PTO), health benefits to include Medical, Dental and Vision and company match 401k. Additional benefits information can be found on our site . **Why Lundbeck** Lundbeck offers a robust and comprehensive benefits package to help employees live well and protect their health, family, and everyday life. Information regarding our benefit offering can be found on theU.S. career site (https://www.lundbeck.com/content/dam/lundbeck-com/americas/united-states/careers/Lundbeck\_Benefits\_Summary.pdf) . _Lundbeck is committed to working with and providing reasonable accommodations to disabled veterans and other individuals with disabilities during our employment application process. If, because of a disability, you need a reasonable accommodation for any part of the application process, please visit theU.S. career site (https://www.lundbeck.com/us/careers/your-job/eeo-accommodations-policy) ._ _Lundbeck is proud to be an equal opportunity workplace. We are committed to equal employment opportunity regardless of race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status, and any other characteristic protected by law, rule, or regulation. Lundbeck participates inE-Verify (https://www.lundbeck.com/content/dam/lundbeck-com/americas/united-states/careers/E-Verify\_Participation\_Poster\_Eng\_Es.pdf) ._ **About Lundbeck** At Lundbeck, our most important contribution is easing the burden of the millions of people living with brain disorders. Whether it is migraine, depression, or other brain disorders, patients, their carers, and society as a whole depend on us. Through cutting edge science and strong partnerships, we develop and market some of the world's leading treatments, expanding into neuro-specialty and neuro-rare from our strong legacy within psychiatry and neurology. The brain health challenge is real. Our commitment is real. Our impact is real. **About Lundbeck** At Lundbeck, our most important contribution is easing the burden of the millions of people living with brain disorders. Whether it is migraine, depression, or other brain disorders, patients, their carers, and society as a whole depend on us. Through cutting edge science and strong partnerships, we develop and market some of the world's leading treatments, expanding into neuro-specialty and neuro-rare from our strong legacy within psychiatry and neurology. The brain health challenge is real. Our commitment is real. Our impact is real.

About the Company

Lundbeck

Lundbeck is a global pharmaceutical company highly committed to improving the quality of life of people living with brain diseases. For this purpose, Lundbeck is engaged in the research, development, manufacturing, marketing and sale of pharmaceuticals across the world. The company’s products are targeted at the disease areas within psychiatry and neurology.

COMPANY SIZE

1,000 to 1,499 employees

INDUSTRY

Other/Not Classified

WEBSITE

https://www.lundbeck.com/global

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