About this Role:
In this role, you will provide scientific expertise in support of Office of Research Innovation, Validation, and Application’s (ORIVA) mission to develop, validate, and apply non-animal approaches and innovative technologies to advance human-centered biomedical research across National Insitutes of Health (NIH). You work directly alongside NIH scientific and program staff across two divisions: D-NICEATM and DAIBR.
Key Responsibilities:
- Evaluate New Approach Methodologies (NAMs) and prepare documentation aligned with guidelines from the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM), FDA, EPA, and the Organization for Economic Co-operation and Development (OECD)
- Design and coordinate interlaboratory validation studies; analyze bioactivity, in vitro/in silico, and dose-response data
- Contribute to study design and provide expert recommendations on data adequacy for government reports and regulatory submissions
- Apply and evaluate computational methods for human health safety and risk assessment
- Review and curate data from relevant scientific databases; perform literature searches in government platforms
- Draft scientific materials including technical reports, research highlights, and meeting summaries
- Support scientific meetings including ICCVAM calls, public forums, and national/international conferences
- Collaborate with NIH scientists, program officers, and cross-functional teams on program deliverables
Qualifications and Skills:
- PhD in a biomedical field (toxicology, pharmacology, cell biology, molecular biology, biochemistry, or related) with 1+ years of relevant experience OR Master's degree in an equivalent field with 4 years of additional experience
- Demonstrated expertise in NAMs or a closely related scientific field
- Experience developing, evaluating, or validating in vitro or computational methods for human health safety or risk assessment
- Strong scientific writing and oral communication skills
- Strong critical thinking, problem-solving, and organizational skills
- U.S. citizenship required; ability to obtain Public Trust clearance
Desired Skills and Competencies:
- Familiarity with 3Rs principles (Replace, Reduce, Refine) and their application in NIH-funded research
- Prior NIH and/or HHS contractor experience
- Peer-reviewed publications in NAMS-related field
Equal Opportunity Employer:
We are an Equal Opportunity Employer and do not discriminate in employment decisions on the basis of race, color, religion, sex (including pregnancy, sexual orientation, or gender identity), national origin, age, disability, genetic information, veteran status, or any other status protected by applicable federal, state, or local laws. All employment decisions are based on business needs, job requirements, and individual qualifications.
Flexible work from home options available.
About Us
Our Approach
We firmly believe in the uniqueness of every business, necessitating a personalized approach to transformation. This conviction drives us to invest time in comprehending an organization's historical challenges and operational framework. Our commitment is to foster innovation by adopting a tailored strategy that optimizes the utilization of an organization's human resources and data assets. With a wealth of experience, we specialize in guiding organizations through the implementation of post-quantum security, protocols for autonomy, and artificial intelligence.
We are committed to working with clients to positively disrupt, modernize, and transform their organizations and business processes. Noteworthy achievements include initiatives aimed at enhancing human resilience in the food supply chain, leveraging autonomy for streamlined operations, establishing root-of-trust capabilities for high-quality, trusted data, and designing ecosystems and tools for securing and transferring digital value through digital wallets. . Our proficiency extends to using artificial intelligence and data to fortify security and enhance visibility in data assets, aiding in the management of health issues at local, state, and national levels. We've developed a modern security posture to effectively mitigate risks associated with cyber attacks from nation-states. Our wealth of experience is underpinned by collaborative work with diverse multidisciplinary teams, thriving in highly complex and rapidly changing environments.