IT Principal, SAP Architect

Alkermes Plc

Waltham, MA

JOB DETAILS
SKILLS
Application Integration, Application Programming Interface (API), Architectural Services, Business Processes, Continuous Improvement, Cross-Functional, Data Migration, Data Processing, Data Quality, Disease, Functional Programming Languages, Leadership, Maintain Compliance, Medical Products, Migration Strategy, Neurology, Neuroscience, Operational Support, Pre-Clinical Development, Problem Solving Skills, Psychiatry and Mental Health, SAP, Team Lead/Manager, Testing
LOCATION
Waltham, MA
POSTED
30+ days ago
  • Own and govern the end-to-end solution architecture for the S/4HANA programme, ensuring alignment across business processes, data, applications, integration, and security.
  • Lead architecture governance and design authority forums; drive decisions, manage exceptions, and resolve cross-stream design gaps, risks, and technical debt.
  • Validate end-to-end solution readiness ahead of go-live, including non-functional requirements (performance, resilience, monitoring, supportability) and operational handover into hypercare.
  • Partner with programme leadership, functional leads, and delivery teams to support cutover planning, environment strategy, data migration validation, and integration sequencing.
  • Engage senior stakeholders and provide architectural leadership across delivery phases; act as escalation point for complex, cross-functional technical issues.
  • Ensure adherence to SAP Clean Core principles and the agreed extensibility strategy; protect the core while enabling continuous improvement.
  • Define and govern BTP-based extensions and integration approaches (SAP Integration Suite/CPI, APIs, event-driven patterns), ensuring secure, scalable, and supportable designs.
  • Oversee integration readiness (build quality, testing, monitoring/alerting, runbooks), ensuring all interfaces are production-ready and operable.
  • Support rapid issue resolution during go-live and early life support, including integration failures, performance issues, and data inconsistencies, coordinating across SAP and non-SAP platforms.
  • Define and transition to a sustainable target architecture and support model, including principles, standards, and a roadmap for post go-live optimisation and innovation.

We are seeking a Prnicpal SAP S/4HANA Solution Architect to provide end-to-end architecture leadership and long-term ownership of the S/4HANA solution landscape. While the programme is approaching go-live in July, the primary focus of this role is to define and govern the target architecture, ensure architectural integrity across all workstreams, and shape the roadmap for ongoing evolution, optimisation, and innovation.

The Solution Architect will provide governance and design assurance across the SAP landscape (process, data, integration, security, and operations), supporting delivery through go-live and establishing a sustainable foundation for steady-state operations. This includes adherence to SAP Clean Core principles and enterprise standards, clear design decision-making, and a forward-looking architecture roadmap, with SAP BTP and SAP Integration Suite/CPI as key enabling components for integration and extensibility.

Why join Team Alkermes?

Alkermes applies its decades of deep neuroscience expertise to develop medicines designed to help people living with complex and difficult-to-treat psychiatric and neurological disorders. A global biopharmaceutical company, headquartered in Ireland with U.S. locations in Massachusetts and Ohio, we seek to make a meaningful difference in the way people manage their diseases. We have a portfolio of proprietary commercial products for the treatment of alcohol dependence, opioid dependence, schizophrenia, bipolar I disorder and narcolepsy, and a pipeline of clinical and preclinical candidates in development for various psychiatric and neurological disorders.

We are proud to have been recognized as an employer of choice by many national organizations. In 2024 and 2025, we were certified as a Great Place to Work in the U.S. and named one of Massachusetts' Top Places to Work by the Boston Globe, a Best Place to Work in Greater Cincinnati by the Cincinnati Business Courier and recognized as a Best Place to Work in BioPharma by Fortune Magazine.

Alkermes, Inc. is an equal employment opportunity employer and does not discriminate against any qualified applicant or employee because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, gender expression and identity, disability, genetic information, veteran status, military status, application for military service or any other characteristic protected by local, state or federal law. Alkermes also complies with all work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Alkermes is an E-Verify employer.

About the Company

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Alkermes Plc