Our client, a Biotech company, is looking for a LNP Formulation Scientist for their San Diego, CA location.
Responsibilities:
Execute and optimize the formulation and characterization of lipid nanoparticles (LNPs) or targeted lipid nanoparticle (tLNPs) encapsulating nucleic acids for in vitro and in vivo studies under the minor guidance of senior formulation scientists.
Implement Design of Experiment (DoE) based screening campaigns to evaluate and establish optimal LNP compositions and processing parameters.
Collaborate cross-functionally with internal teams to support and fulfill formulation requests.
Support early-stage formulation development and downstream processing activities when needed, including cryoprotection, scale-up, and stability studies.
Maintain detailed records documenting formulation activities and results.
Analyze, interpret, and present experimental data to the formulation team.
Contribute to routine lab management activities, including inventory tracking, supply ordering, buffer preparation, and autoclaving.
Requirements:
Education: Bachelor’s degree in Chemistry, Biochemistry, Chemical Engineering, or a related discipline with 4+ years of biopharma industry experience, OR a Master’s degree with 1+ years of industry experience.
LNP Expertise: Minimum of 2 years of hands-on laboratory experience specializing in LNP formulation and encapsulation of nucleic acids (mRNA, siRNA, or DNA).
Analytical Skills: Proficiency with standard LNP characterization methods, including Dynamic Light Scattering (DLS), Zeta potential, and Ribogreen assays.
Software & Data: High proficiency in MS Excel is required; hands-on experience with statistical and data analysis software (e.g., JMP, Prism) is preferred.
Core Competencies: Strong attention to detail, a track record of producing reproducible data, excellent organizational skills, and the ability to communicate effectively within a fast-paced team environment.
Preferred Skills: Prior experience with targeted LNP preparation (mAb, Fab, ScFv, VHH coated LNP) and immune cell delivery is highly desirable.
ICONMA is a global information consulting management firm providing Professional Staffing Services and Project-Based Solutions for organizations in a broad range of industries.
Corporate Headquarters in Troy, Michigan; 20+ locations worldwide.
Certified Woman-Owned Business Enterprise (WBE); certified by Women’s Business Enterprise National Council, National Women Business Owners Corporation (NWBOC); and California Public Utilities Commission (CPUC).
Founded in 2000
2000+ Employees
The company was founded on the principle that success is derived from delivering high quality service and resources in the most responsive, flexible, and innovative way. ICONMA invests in people and resources with a single goal: To provide our customers with the highest quality service in the most responsive manner. Through its network of offices, ICONMA provides the resources to help clients maintain their competitive advantage.
Skills
Analysis Skillsunmatched
Assaysunmatched
Autoclaveunmatched
Biochemistryunmatched
Biotech and Pharmaceuticalunmatched
Campaignsunmatched
Chemical Engineeringunmatched
Chemistryunmatched
Communication Skillsunmatched
Cross-Functionalunmatched
DNAunmatched
Data Analysisunmatched
Detail Orientedunmatched
Documentationunmatched
Experiment Designunmatched
Health Planunmatched
Laboratoryunmatched
Laboratory Managementunmatched
Microsoft Excelunmatched
Nucleic Acidunmatched
Organizational Skillsunmatched
Prismunmatched
Record Keepingunmatched
Statistical Analysis System (SAS)unmatched
Statisticsunmatched
Statistics Softwareunmatched
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