Manufacturing Operator – GMP Production

Onsite | St. Joseph, MO | 12-Month Contract | 1st Shift (7:00 AM–3:30 PM)

Sigma Systems is seeking a Manufacturing Operator to support a leading manufacturing operation in St. Joseph, Missouri. This 12-month contract opportunity is ideal for candidates with experience in manufacturing, production operations, machine operation, GMP environments, equipment operation, and quality-focused production processes.

The Manufacturing Operator will operate production equipment, follow standardized procedures, complete accurate documentation, and support manufacturing activities in compliance with Good Manufacturing Practices (GMP), safety guidelines, and Standard Operating Procedures (SOPs).

Job Responsibilities

• Operate general manufacturing equipment under supervision while following current GMP requirements and standardized procedures
• Perform manufacturing activities according to established SOPs and safety guidelines
• Complete accurate production documentation and maintain detailed records
• Support manufacturing processes including:
  • Fermentation
  • Protein purification
  • Solvent extractions
  • Tissue culture
  • Bulk solution preparation
  • Buffer and media preparation
  • Filtration processes
  • Aseptic buffer fills
  • Vial preparation and sterilization
  • Vial filling and labeling under sterile and non-sterile conditions
• Monitor equipment operation and ensure processes are completed according to specifications
• Identify and communicate process deviations or issues to supervisors
• Maintain a clean, safe, and organized manufacturing environment
• Follow all safety procedures and quality requirements
• Support production goals while maintaining accuracy and attention to detail

Required Qualifications

• High School Diploma or equivalent
• Previous experience in:
  • Manufacturing
  • Production operations
  • Machine operation
  • Equipment operation
• Strong attention to detail and documentation skills
• Ability to follow written procedures and SOPs
• Good mechanical aptitude and ability to operate manufacturing equipment
• Ability to lift up to 35 pounds
• Ability to work effectively in a team-oriented production environment

Preferred Qualifications

• Experience working in a GMP, pharmaceutical, biotechnology, medical device, or regulated manufacturing environment
• Experience with:
  • Sterile manufacturing
  • Aseptic processing
  • Filling and labeling operations
  • Laboratory manufacturing processes
  • Production documentation
• Experience following strict quality and compliance procedures

Schedule

• Monday–Friday
• 1st Shift: 7:00 AM–3:30 PM
• 40 hours per week

Contract Details

• Job Title: Manufacturing Operator
• Location: St. Joseph, MO
• Duration: 12-Month Contract
• Work Arrangement: Onsite
• Schedule: Full-Time, 1st Shift