Summary: The Molecular and Cellular Biologist will support efforts to apply multi-omics & systems biology approaches to improve mammalian cell culture performance for the production of recombinant proteins.
Job Responsibilities:
Design and execute molecular and cellular biology experiments involving the transfection, passaging, and sampling of CHO cell cultures to generate substrate for multi-omics analyses.
Design and execute experiments to examine gene copies, transcript levels, protein folding, assembly, trafficking, secretion, and degradation. Analyze and interpret data using statistical, bioinformatics, and pathway-analysis tools.
Document findings and prepare technical reports, presentations, and manuscripts. Collaborate with cell-line development scientists, bioprocess engineers, analytical scientists, and computational biologists. Comply with laboratory safety and data-integrity requirements.
Familiarity with multi-omics study design, bioinformatics, statistical analysis, and systems biology. Strong understanding of molecular cell biology fundamentals including DNA replication, transcription, translation, proteostasis, metabolism, cellular stress mechanisms, and their relation to recombinant protein production.
Effective written and verbal communication. Ability to work well and collaboratively within multidisciplinary teams. Strong attention to experimental rigor, documentation, reproducibility, and scientific integrity.
Qualification:
Bachelor’s or master’s degree in molecular biology, cell biology, biochemistry, biotechnology, bioengineering, systems biology, or a related field required.
Zero to two years of relevant laboratory or biotechnology-industry experience.
Experience with mammalian and/or CHO cell culture, antibody production, multi-omics technologies, molecular perturbation methods, and regulated laboratory environments is preferred.
Pay Transparency: The typical base pay for this role across the U.S. is: $27.35 - $30.10/hr. Non-exempt positions are eligible for overtime at a rate of 1.5 times the base hourly rate for all hours worked in excess of 40 in a work week, or as required by state or local law. Final offer amounts, within the base pay set forth above, are determined by factors including your relevant skills, education and experience. Full-time employees are eligible to select from different benefits packages. Packages may include medical, dental, and vision benefits, health savings accounts with qualified medical plan enrollment, 10 paid days off, 3 days paid bereavement leave, 401(k) plan participation with employer match, life and disability insurance, commuter benefits, dependent care flexible spending account, accident insurance, critical illness insurance, hospital indemnity insurance, accommodations and reimbursement for work travel, and discretionary performance or recognition bonus. Sick leave and mobile phone reimbursement provided based on state or local law.
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#AditiConsulting #26-05985
Numbers & Facts
Location
Andover, MA
Salary
$27.35–$30.10 Per Hour
Skills
Analysis Skillsunmatched
Antibodiesunmatched
Artificial Intelligence (AI)unmatched
Asepsisunmatched
Automotive Automationunmatched
Biochemistryunmatched
Bioengineeringunmatched
Bioinformaticsunmatched
Biologyunmatched
Biotech and Pharmaceuticalunmatched
Cell Biologyunmatched
Cell Culturesunmatched
Cloningunmatched
Communication Skillsunmatched
Consultingunmatched
Cross-Functionalunmatched
DNAunmatched
DNA Replicationunmatched
DNA Sequencingunmatched
Data Analysisunmatched
Data Qualityunmatched
Documentationunmatched
Experiment Designunmatched
Messaging Technologyunmatched
Microscopyunmatched
Molecular Analysisunmatched
Molecular Biologyunmatched
Polymerase Chain Reaction (PCR)unmatched
Presentation/Verbal Skillsunmatched
Problem Solving Skillsunmatched
Purchasing/Procurementunmatched
Real-time PCR (qPCR)unmatched
Reporting Skillsunmatched
Safety Complianceunmatched
Short Messaging Service (SMS)unmatched
Speech Technologyunmatched
State Laws and Regulationsunmatched
Statistical Analysis System (SAS)unmatched
Statisticsunmatched
Technical Presentationunmatched
Telephonyunmatched
Writing Skillsunmatched
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