Oligonucleotide Scientist II

Aptask Global Workforce (AGW) is seeking an Oligonucleotide Scientist II for a fully on-site position with a Global Biotechnology Company located in South San Francisco, CA. This is a 5+ month contract opportunity.

We are seeking a creative, self-motivated, and collaborative scientist to join the Nucleic Acid Design and Discovery (NADD) team. The successful candidate will have experience in oligonucleotide discovery and synthesis to support a new oligonucleotide therapeutics discovery group. This role will contribute to an interdisciplinary chemistry team working in RNAi biology research and will interface across different therapeutic areas, including neuroscience, immunology, and oncology.

Key Responsibilities:

• Work in an oligonucleotide therapeutic drug discovery research lab and interface across different therapeutic areas
• Troubleshoot oligonucleotide synthesis and impurity profiling
• Collaborate with other scientists to maintain common lab equipment such as oligo synthesizers, HPLC and desalting units
• Perform literature reviews, propose, and execute nucleic acid chemistry plans
• Coordinate chemistry and biology data to support oligonucleotide compound progression
• Establish methods for scaled-up synthesis of lead molecules and coordinate material delivery for preclinical studies
• Maintain a high level of productivity in the laboratory setting to meet the timelines for in vitro and in vivo studies

Requirements:

• BS/MS in Organic Chemistry or related discipline
• Hands-on experience in oligonucleotide synthesis using automated oligo synthesizers, nucleic acid chemistry, oligonucleotide purification and characterization using HPLC and mass spectrometry
• Strong problem-solving, analytical, communication and organizational skills
• Good communication and interpersonal skills

Desired skills:

• Pharmaceutical or biotechnology industry experience in research and development of RNAi therapeutics
• A good understanding of nucleic acid therapeutic modalities, modification chemistries, sequence selection, and mechanism of action
• Relevant experience in oligonucleotide therapeutics, large molecule drug discovery, oligonucleotide delivery or bio-conjugation

Pay range: up to $53.58 per hour

Only candidates available and ready to work directly as Aptask Global Workforce (AGW) employees will be considered for this position.

If you have the described qualifications and are interested in this exciting opportunity, apply today!

Aptask Global Workforce (AGW)
ApTask Global Workforce (AGW) is a certified Minority and Veteran workforce solutions company. AGW delivers operational, clinical, lab and professional talent with a strong focus on healthcare and life sciences. The company supports clients with reliable staffing, program expertise and a commitment to quality, speed and consistent delivery.

Benefits of working with ApTask Global Workforce include:

• Medical
• Dental
• Vision
• Sick Pay (for applicable states/municipalities)

Our team stays close to the process and is here to guide you every step of the way. To learn more, please visit our website https://www.agwtalent.com/. 

ApTask Global Workforce is an Equal Opportunity Employer. Candidates will receive consideration without regard to their race, color, religion, sex, sexual orientation, gender identity, national origin, disability or status as a protected veteran.

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