Post Doctoral Associate (Ebright Lab)

Position Details Position Information RecruitmentPosting Title Post Doctoral Associate Ebright Lab Department Waksman Institute of Microbiology Salary Details 63968.00 Offer Information The final salary offer may be determined by several factors including but not limited to the candidates qualifications, experience, and expertise, and availability of department or grant funds to support the position. We also take into consideration market benchmarks if and when appropriate and internal equity to ensure fair compensation relative to the universitys broader compensation structure. We are committed to offering competitive and flexible compensation packages to attract and retain top talent.

Benefits Rutgers provides a comprehensive benefits package to eligible employees. The specific benefits vary based on the position and may include:

• Medical
• Prescription drug
• Dental coverage
• Paid vacation
• Holidays
• Various leave programs
• Competitive retirement benefits including defined contribution plans and voluntary tax-deferred savings options
• Employee and dependent educational benefits when applicable
• Life insurance coverage
• Employee discount programs

Posting Summary This position conducts research on RNA polymerase structure and function and on small-molecule inhibitors of RNA polymerase in the Richard Ebright Lab. The responsibilities include:

• Using cryo-ET, cryo-EM, and X-ray crystallography to define structures and structural transitions of transcription complexes and transcription-translation complexes
• Identifying and characterizing small-molecule inhibitors of transcription
• Preparing and assaying proteins and nucleic acids
• Preparing and assaying ribosomes
• Preparing text tables and figures for patent applications and publications
• Presenting results at scientific meetings

Responsibilities The successful candidate will:

• Perform professional-level experiments and research using various techniques
• Carry out routine and non-routine work with review of work outputs by supervisor
• Document work performed and maintain a notebook and database
• Communicate effectively with supervisor
• Use and help maintain highly specialized equipment
• Maintain and keep the workplace and laboratory organized in a clean and safe manner in accordance with established procedures
• Train and lead research staff, postdoctoral associates, students, and technicians in laboratory-related activities

Position Status Full Time Posting Number 25FA0757 Posting Open Date Posting Close Date

Qualifications Minimum Education and Experience Requires a doctorate in biochemistry, molecular biology, or an allied field. Requires in-depth understanding and hands-on experience in preparation and analysis of proteins, nucleic acids, and complexes thereof. Requires in-depth understanding and hands-on experience in molecular cloning, sequencing, and site-directed mutagenesis. Requires in-depth understanding and hands-on experience in cryo-EM, cryo-ET, and/or X-ray crystallography, including sample preparation, data collection, and data processing.

Preferred Qualifications

• In-depth understanding and hands-on experience in cryo-EM and/or cryo-ET, including sample preparation, data collection, and data processing
• Experience in structural and functional analysis of RNA polymerase and transcription complexes and/or ribosomes and translation complexes
• Effective spoken and written English
• High level of computer literacy
• Experience in chromatography, including FPLC and preferably HPLC and electrophoresis
• Experience in work with chemical hazards and radiological hazards
• Experience in work with biological hazards, biosafety levels 1 and 2

Certifications Licenses Knowledge, Skills, and Abilities Physical Demands and Work Environment Average to above-average levels of mobility expected for laboratory environment. Average to above-average levels of upper-body strength expected for lifting and working with bioreactors, large-volume culture flasks, Dewar flasks, cryo reservoirs, and other heavy items.

Level of Decision Making The individual should be able to cope with the highly complex, highly unpredictable nature of scientific research and with the management challenges posed by a large and diverse scientific research team. The incumbent is expected to attempt to resolve problems in long-term, mid-term, and day-to-day experimentation and management by thinking, researching, and seeking advice, and then making recommendations to the PI.

Statement Posting Details Special Instructions to Applicants Quick Link to Posting https://jobs.rutgers.edu/postings/257649 Campus Rutgers University-New Brunswick Home Location Campus Rutgers University - New Brunswick City Piscataway State NJ Location Details Waksman Institute of Microbiology 190 Frelinghuysen Rd Piscataway

Pre-employment Screenings All offers of employment are contingent upon successful completion of all pre-employment screenings.

Immunization Requirements Under Policy 100.3.1 Immunization Policy for Covered Individuals, if employment will commence during Flu Season, Rutgers University may require certain prospective employees to provide proof that they are vaccinated against Seasonal Influenza for the current Flu Season, unless the University has granted the individual a medical or religious exemption.

Additional infection control and safety policies may apply. Prospective employees should speak with their hiring manager to determine which policies apply to the role or position for which they are applying. Failure to provide proof of vaccination for any required vaccines or obtain a medical or religious exemption from the University will result in rescission of a candidates offer of employment or disciplinary action up to and including termination.

Equal Employment Opportunity Statement It is university policy to provide equal employment opportunity to all its employees and applicants for employment regardless of their race, creed, color, national origin, age, ancestry, nationality, marital or domestic partnership or civil union status, sex, pregnancy, gender identity or expression, disability status, liability for military service, protected veteran status, affectional or sexual orientation, atypical cellular or blood trait, genetic information, including the refusal to submit to genetic testing, or any other category protected by law. As an institution, we encourage all qualified applicants to apply. For additional information, please see the Non-Discrimination Statement at the following web address: http://uhr.rutgers.edu/non-discrimination-statement

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