374932true374932falseSubmission for the position Post Doctoral Fellow - Rockefeller Neuroscience Institute Department of Neuroscience - Job Number 29029false374932falsetruePost Doctoral Fellow - Rockefeller Neuroscience Institute Department of Neuroscience 29029
The Rockefeller Neuroscience Institute Department of Neuroscience at West Virginia University is currently accepting applications for a Post Doctoral Fellow.
About the Opportunity Postdoctoral fellowship in synaptic biology and super-resolution imaging in models of Alzheimers disease.
The Hruska Laboratory in the Department of Neuroscience at the West Virginia University School of Medicine is recruiting a postdoctoral researcher to join an exciting fully funded program supported by the National Institute on Aging NIA. This position offers an outstanding opportunity to lead a high-impact project investigating the molecular architecture of synapses using advanced approaches including STED super-resolution microscopy.
Our work seeks to uncover core mechanisms that govern synapse function and plasticity with a particular focus on nanoscale organization of dendritic spines. We aim to understand how these highly organized molecular structures become disrupted in Alzheimers disease AD and how these structural changes translate into synaptic dysfunction reduced plasticity circuit instability and ultimately cognitive decline and memory impairment.
Our recent findings reveal striking synapse-specific vulnerability to amyloid-beta A suggesting the existence of an underlying molecular logic that remains to be defined. To uncover these mechanisms we integrate molecular biology biochemistry CRISPR-based genome engineering and advanced imaging in living and fixed neurons directly linking nanoscale synaptic organization to functional outcomes.
We are seeking a highly motivated intellectually curious and creative scientist who is eager to lead an ambitious project. The successful candidate will hold a Ph.D. in neuroscience or molecular and cellular neurobiology have at least one first-author publication in a peer-reviewed international journal and possess strong expertise in molecular and cellular neuroscience.
Candidates who are about to complete their Ph.D. are encouraged to apply. The ideal applicant is independent rigorous and excited to build a research program that connects molecular cellular and circuit-level neuroscience.
Department of neuroscience offers a highly collaborative intellectually vibrant and deeply supportive scientific environment with access to state-of-the-art infrastructure. Hruska laboratory is committed to mentorship career development and fostering scientific independence.
This position is fully funded ensuring long-term stability and continuity for the project. At the same time we actively encourage and support the successful candidate in applying for competitive fellowships as part of their professional growth and transition toward research independence.
For details about the position please reach out directly to Dr. Martin Hruska martin.hruskahsc.wvu.edu.
We strongly believe in work-life balance and keeping time for things we love outside our work. WVU offers generous benefits including:
• 37.5-hour work week • 13 paid holidays • 24 annual leave vacation days per year • 18 sick days per year for when youre ill for when you need time to care for sick family for your own or your familys regularly scheduled medical appointments. • Who is family for the purpose of this leave? A lot of people in your life including immediate relatives and in-laws as well as others considered to be members of your household living under the same roof • WVU offers a range of health insurance and other benefits • 401a retirement savings with 6 employee contribution match eligibility to continue health insurance and other retiree perks. • Looking for more retirement benefits information? Check out retirement health insurance benefits retirement income and FAQs. • Wellness programs
What Youll Do • Design plan and execute experiments using advanced imaging techniques e.g. confocal STED. • Prepare and process biological samples for imaging e.g. tissue sections cell cultures. • Perform image acquisition processing and quantitative analysis using specialized software. • Manipulate and analyze protein or RNA expression using molecular tools to test hypotheses • Collaborate with lab members to interpret data and troubleshoot experiments. • Contribute to manuscript writing grant preparation and presentation of results. • Maintain detailed and organized records of experimental procedures and results. • Present findings at national and international conferences • Maintain high standards of laboratory organization rigor reproducibility and academic integrity
Knowledge, Skills, and Abilities Preferred Qualifications Knowledge, Skills, and Abilities Preferred Qualifications
Required Certifications may be completed after hire • CITI Biohazards training certificate • CITI animal training certificate • CITI Conflict of Interest in Research certificate
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