Post Doctoral Scholar

Department Overview:

A postdoctoral scholar position with a competitive salary and excellent benefits is available in the Shi Laboratory at the Oregon Hearing Research Center (OHRC) in the Department of Otolaryngology-Head & Neck Surgery. Individuals who hold a PhD with significant mouse auditory physiology and molecular biology experience are especially qualified to apply. The main focus of the Shi lab is animal research on auditory pathophysiology, gene therapy, cellular and molecular biology. The OHRC is one of the world's leading hearing-science research groups. Expertise in the OHRC spans from basic to translational science, and from the inner ear to the auditory cortex. The research focus of OHRC investigators ranges from fundamental mechanisms of hearing to development of therapies for hearing loss.

Function/Duties of Position:

• Harvesting cochlear tissues, and immunohistochemistry, confocal imaging, PCR and RT-PCR analysis requiring mastery of complex principles and practices.

• Measurement of blood flow with intravital fluorescence microscopy based on lab established protocol and the measurement of auditory function with auditory brainstem response. 

• Animal husbandry to maintain mouse colonies, and genotyping of transgenic mice.

• Administration of agents to animals through fine animal surgery (e.g. semicircular canal surgery)

• Analysis and reporting of data. 

• Write scientific papers and present data at scientific conferences.

• Additional responsibilities include the maintenance of lab operations such as placing animal orders and detailed record keeping.

• Will help to train and supervise junior research fellows on a variety of protocols established in the Shi lab (e.g., how to isolate the whole mount of cochlear tissues, cell culture and immunohistochemistry, and real-time PCR etc). Will help to coordinate research activities both independent and collaborative projects for all lab staff.

Required Qualifications:

• PhD

• Knowledge of animal physiology and biology

Preferred Qualifications:

• A few years in a laboratory setting, with previous experience with animal physiology,  gene transfer, transgenic mouse husbandry, tissue dissection, cell culture and immunohistochemistry and confocal imaging, data collection, basic molecular biological methods (Western blot, PCR), and data analysis and representation of results at scientific meetings.
• Experience with vascular biology

Why apply to OHSU?: We are Oregon's only public academic health center. In addition to caring for patients, we lead groundbreaking research. We also train the next generation of health care professionals. As Portland's largest employer, we give you opportunities to learn and advance in a system of hospitals and clinics across Oregon and Southwest Washington. All are welcome. OHSU welcomes people of all ages, ethnicities, genders, national origins, religions and sexual orientations. We are striving to build an anti-racist, multicultural institution and encourage people with diverse backgrounds to apply. To request reasonable accommodation, contact askhr@ohsu.edu