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Postdoctoral Fellow - Diabetes, Inflammation, Hard and Soft Tissue Healing

University of Pennsylvania

Philadelphia, PA

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JOB DETAILS
SKILLS
Analysis Skills, Assays, Bioinformatics, Cell Analysis, Cell Cultures, Communication Skills, Conferences, Data Sets, Detail Oriented, Diabetes, Experiment Design, Genetics, Grant Writing, Histology, Identify Issues, Journalism, Laboratory Management, Leadership, Mentoring, Molecular Analysis, Next Generation Sequencing (NGS), Polymerase Chain Reaction (PCR), Protocol Design, Quality Control, Quantitative Analysis, Real-time PCR (qPCR), Regulations, Scientific Publications, Seminars, Storytelling, Team Player, Translational Research
LOCATION
Philadelphia, PA
POSTED
21 days ago


Faculty Mentor: Dana Graves, DDS DMSc



Department: Periodontics



Funding Source: Grant Funded



Number of Positions: 1



Open to applications from U.S. Citizens and foreign nationals



We are seeking an energetic Postdoctoral Fellow to join a fast-paced, highly collaborative laboratory investigating how diabetes reshapes immune regulation, cellular signaling, and hard and soft tissue healing. This role is designed for a hands-on, intellectually curious scientist who wants to take ownership of impactful projects while accelerating career growth through publication-driven science, mentorship, and leadership opportunities. You will work closely with faculty and trainees in a supportive, high-productivity environment with clear opportunities to build a strong track record in manuscripts, grant writing, conference presentations, and translational experimental design, positioning you competitively for the next step in academia, clinical and translational research, or industry. Strong communication skills, reliability, attention to detail, and enthusiasm for learning are essential







In this position, you will drive projects from concept to completion by contributing to experimental design, protocol development and optimization, execution, troubleshooting, and data interpretation across integrated in vivo and in vitro platforms. Experimental work will include translational studies in genetically modified mouse models, in vivo inhibitor approaches, and immune and tissue phenotyping to define how diabetes alters inflammation and repair, including mechanistic studies of wound healing involving soft tissue or bone, innate and adaptive immune responses and key immune-cell interactions such as dendritic cells and lymphocytes. You will apply a core toolkit spanning primary immune cell isolation and culture, functional immune assays, flow cytometry (panel design, staining optimization, acquisition, gating, and quantitative analysis), molecular and signaling assays (e.g., PCR and qPCR, pathway and protein readouts, reporter assays), and tissue-level analyses (histology, immunofluorescence or immunohistochemistry, and image-based quantification). A major emphasis of the role is cutting-edge transcriptomic research, including next-generation sequencing workflows such as bulk RNA-seq, single-cell RNA-seq, and spatial transcriptomics, with opportunities to integrate these datasets with mechanistic wet-lab findings. The successful candidate will contribute to bioinformatics and computational analysis, including quality control, alignment and quantification, differential expression, pathway and network enrichment, cell type annotation, trajectory and cell state analyses, and multi-modal integration across transcriptomics, flow cytometry, and tissue imaging. The fellow will actively contribute to manuscripts and grant applications through figure generation, methods and results drafting, data synthesis, and scientific storytelling, while also developing leadership skills through mentoring and supervision of lab members and presenting findings at internal seminars and national or international conferences as projects mature.



Eligibility for appointment as a postdoc requires candidates to hold, or to have completed the requirements fir an advanced degree e.g. PhD, MD or equivalent. Candidates from non U.S. universities must hold advanced degrees equivalent to thos awarded in the U.S. Institutions to qualify for appointment as postdoctoral fellow.



Applicants must submit a CV, cover letter, and contact information for three professional references. All materials must be submitted through Interfolio.




The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state, or local law.

About the Company

U

University of Pennsylvania

Penn's beautiful urban campus provides easy access to a range of educational, cultural, and recreational activities. We offer excellent healthcare and tuition benefits for you and your family, as well as generous retirement benefits, professional development opportunities and flexible work options. Penn is a diverse, multicultural learning community at the cutting edge of research and information technology. Click here to read more about why we're a Best Employer. Not only does Penn offer a unique environment within the city of Philadelphia to work, we also provide a wide array of employee benefits. From a competitive retirement program and comprehensive health care options to health promotion and wellness services and tuition assistance, there's a wealth of opportunities and resources available to you at Penn.

Penn is frequently cited as an outstanding employer:

  • Recipient of the 2010 Terri Lynne Lokoff Child Care Foundation Corporate Leadership Award for commitment to supporting worklife balance programs.
  • Selected as a recipient of the 2010 Healthy Workplace Award by the Philadelphia Business Journal and presenting sponsor UnitedHealthcare
  • Recognized as a 2010 Top Workplace by The Philadelphia Inquirer/Daily News.
  • Recipient of the 2009 Vision Award for commitment to workforce diversity and economic inclusion.
  • Selected for Computerworld's 100 Best Places to Work in IT six years in a row!
  • Recognized by the Delaware Valley Association for the Education of Young Children as a 2006 Best Employer for Working Parents
  • Named a Best Place to Work in the November 2007 issue of Philadelphia Magazine.
  • Designated a Best Workplace for Commuters by the National Center for Transit Research
COMPANY SIZE
100 to 499 employees
INDUSTRY
Advertising and PR Services
FOUNDED
1990
WEBSITE
http://www.cmimedia.com/

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