Join the forefront of groundbreaking research at City of Hope where we''re changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.
The Beckman Research Institute of City of Hope is seeking a highly motivated Postdoctoral Fellow to join Dr. Jen Jen Yeh's laboratory. The laboratory aims to understand the pathogenesis and pharmacogenomics of pancreatic cancer in order to accelerate treatment. Using a combination of molecular and genomic data and human-in-mouse models, the lab has identified four core subtypes in pancreatic cancer with important biologic and clinical implications.
As a successful candidate you will:
Focus on cancer genomics and personalized medicine, with responsibilities that include computational method development, data analysis, and experimental design.
Integrate information from high-throughput screens, proteomic data, and next-generation sequencing data to generate and validate hypotheses of therapeutic relevance to pancreatic cancer.
Your qualifications should include:
Ph.D. in Bioinformatics, Genetics, Genomics, or an equivalent field.
Experience with common experimental techniques in molecular biology.
Experience working with mouse models.
Experience handling large datasets.
Thorough understanding of common statistical tests and distributions.
Ability to collaborate with experimental and computational team members.
Comfort maintaining datasets, as well as displaying and interpreting processed data for publication.
Demonstrated independence in developing new methods and troubleshooting.
Ability to communicate scientific material and collaborate well with computational and non-computational partners.
Excellent oral and written communication skills and the ability to perform both self-directed and guided research.
Outstanding personal initiative and the ability to work effectively as part of a team.
Willingness to assist in the mentorship and training of pre-doctoral researchers.
Knowledge of rigor and reproducibility best practices.
Preferred qualifications:
Thorough knowledge of cancer biology, epigenetics, proteomics, and transcriptomics.
Familiarity with next-generation sequencing data analysis tools.
Experience working in Linux environments, including batch job management on shared computing resources.
Familiarity with a variety of supervised and unsupervised classification techniques.
Proficiency in one or more statistical or scripting languages, preferably R or MATLAB.
Knowledge of survival-based statistical analysis, such as Cox regression and Kaplan-Meier analysis.
Working knowledge of machine learning best practices to avoid overfitting.
City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.
City of Hope is an equal opportunity employer.
To learn more about our Comprehensive Benefits, please CLICK HERE.
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| Location | Duarte, CA |