Postdoctoral positions are available in the laboratory of Dr. Srinivas Malladi Ph.D. - Faculty Profile - UT Southwestern Department of Pathology at UT Southwestern Medical Center to study metastatic dormancy and recurrences in breast lung and renal adenocarcinomas.
Malladi Lab - UT Southwestern Dallas, Texas, is focused on developing improved diagnostic and therapeutic modalities for treating residual disease and metastasis. We employ molecular, biochemical, immunologic, genomic, imaging, and computational-based techniques to understand the biology of latent and overt metastasis in breast and kidney cancers using mouse models, xenografts, and patient samples.
Recent Publications
• Metabolic adaptations of brain metastasis. Nature Reviews Cancer 2025. • AXLWRNIP1 mediates replication stress response and promotes therapy resistance and metachronous metastasis in HER2 breast cancer. Cancer Research 2024. • Limiting mitochondrial plasticity by targeting DRP1 induces metabolic reprogramming and reduces breast cancer brain metastases. Nature Cancer 2023. • Cell competition shapes metastatic latency and relapse. Cancer Discovery 2023. • Metabolic diversity within breast cancer brain-tropic cells determines metastatic fitness. Cell Metabolism 2022.
Candidates must hold a recent Ph.D. and/or M.D. degree. Prior research experience with Cancer biology, mouse models, organoids, epigenetics, CRISPR screens, microscopy, and bioinformatics will be highly regarded. A track record of productivity and publications in peer-reviewed journals is essential.
Information on our postdoctoral training program, benefits, and a virtual tour can be found at http://www.utsouthwestern.edu/postdocs.
Interested individuals should send a CV and statement of interest to Srinivas Malladi Ph.D. at UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9072, Srinivas.Malladi@utsouthwestern.edu, http://labs.utsouthwestern.edu/malladi-lab, https://profiles.utsouthwestern.edu/profile173686/srinivas-malladi.html.
Interested individuals must upload a CV, cover letter, and a list of three references.
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.
Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full-time schedule.
To learn more about the benefits UT Southwestern offers, visit http://www.utsouthwestern.edu/employees/hr-resources.
Benefits
UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing and include:
• PPO medical plan available day one at no cost for full-time employee-only coverage • 100 coverage for preventive healthcare - no copay • Paid Time Off available day one • Retirement Programs through the Teacher Retirement System of Texas (TRSP) • Paid Parental Leave Benefit • Wellness programs • Tuition Reimbursement • Public Service Loan Forgiveness (PSLF) Qualified Employer
Learn more about these and other UTSW employee benefits.