Postdoctoral Scholar (Department of Radiation Oncology)

Position Details

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Position Information

Job Title Postdoctoral Scholar (Department of Radiation Oncology) Department Name 311750000 Radiation Oncology Chair Office School/College School of Medicine Job Description

CANCER IMMUNOTHERAPY & RADIOTHERAPY RESEARCH

Postdoctoral Scholars

Department of Radiation Oncology and O'Neal Comprehensive Cancer Center,

University of Alabama at Birmingham (UAB)

Job Description: Postdoctoral Scholarships are available in our lab with a focus on defining T

cell-intrinsic mechanisms of cancer immunotherapy and radiotherapy. Specifically, we want to

identify new targets for cancer interventions that can be leveraged to overcome immunotherapy

resistance and prolong therapeutic effects of radiotherapy. Please refer to our publications for

further information (Cell, 2016; Nat. Med., 2017; Nat. Comms., 2016, 2022, 2024, 2025). Another

research area in our lab is T cell immuno-metabolism, where we published a couple of the initial

studies (JEM, 2011; Immunity, 2011), with both been cited for over 2000 times. Our experimental

models include genetically modified mice and disease models for various types of cancer,

autoimmune diseases, infections, and inflammation. Our lab has been funded by NIH (R01, R21),

DoD (Idea Award), Cancer Research Institute, V Foundation, Varian Medical System, and UAB

O'Neal Invests pre-R01 grants.

Our findings have been highlighted by UAB Featured Discovery

and Research & Innovation:

https://www.uab.edu/medicine/news/featured-discovery/selective-suppression-of-melanomalacking-

ifn-pathway-by-jak-inhibition-depends-on-t-cells-and-host-tnf-signaling

https://www.uab.edu/medicine/news/featured-discovery/shi-recognized-for-discovery-in-tumorrelated-

immune-regulation

https://www.uab.edu/medicine/radonc/news-events/department-news/shi-appointed-inauguralholder-

of-koikos-petelos-jones-bragg-roar-professorship

https://www.uab.edu/news/research/item/13111-melanoma-treatment-potential-target-bypassestherapeutic-

resistance-to-immune-checkpoint-blockers

https://www.uab.edu/medicine/radonc/news-events/department-news/new-research-identifiesstrategy-

to-overcome-icb-resistance-in-melanoma-patients

Required Qualifications

Highly motivated recent Ph.D. and/or M.D. with strong molecular biology

and/or immunology skills are encouraged to apply. Please send a CV, including contact

information for three references, to lewisshi@uabmc.edu or lshi@uab.edu.

Preferred Qualifications

Posting Detail Information

Posting Number PF1023P Open Date 05/28/2026 Close Date Open Until Filled No Nondiscrimination Statement

UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, religion, and veteran's status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.

Special Instructions for the Position Pre-employment Background Check

A pre-employment background check investigation is performed on candidates selected for employment.

About University of Alabama at Birmingham

Supplemental Questions

Required fields are indicated with an asterisk (*).

• Did you do a postdoctoral program at another institution?

(Open Ended Question)

Documents Needed to Apply

Required Documents

• Curriculum Vitae
• Graduate Transcripts (Unofficial Only)

Optional Documents