Principal Scientist - Mass Spec Bioanalysis Production (LC-MS/MS)

As a Principal Scientist at KCAS Bio, you will serve as the senior scientific authority within the assigned business unit, providing strategic leadership and ultimate accountability for the scientific quality and integrity of all assigned studies.
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You will lead end-to-end study oversight—including study design, method development, validation, execution, data interpretation, and reporting—ensuring alignment with the highest standards of scientific rigor, regulatory compliance, and data integrity.
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In this role, you will act as a recognized subject matter expert, shaping scientific strategy, establishing best practices, advancing innovation, and mentoring the next generation of scientific leaders, while representing KCAS Bio as a trusted scientific partner to clients, sponsors, and the broader scientific community.
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In this role, we will rely on you to:

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• Serve as the final scientific authority for complex bioanalytical validations and biostudies, providing oversight and approval of scientific strategy, execution, and interpretation.
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• Set scientific direction and standards within the business unit to ensure consistent, high‑quality scientific output across programs.
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• Provide strategic oversight of method development, validation, and study execution, particularly for complex or high‑risk programs.
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• Independently review, interpret, approve, and communicate study results with scientific staff, sponsors, and internal leadership.
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• Provide high‑level scientific leadership in sponsor meetings, regulatory interactions, audits, and scientific defense of study data.
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• Lead the evaluation, adoption, and integration of new technologies and methodologies aligned with long‑term organizational strategy.
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• Direct and manage scientific staff, including workload prioritization, performance evaluations, salary reviews, mentoring, and succession planning.
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• Develop and elevate scientific capabilities of the organization through coaching, training, and leadership development of senior scientific staff.
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• Ensure effective cross‑functional communication and collaboration to align expertise and solve complex analytical challenges.
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• Author, review, and approve high‑impact scientific documents, protocols, and final reports.
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• Represent KCAS Bio at scientific conferences and professional meetings through presentations, posters, or invited talks to maintain external scientific visibility.
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• Ensure proper archiving and documentation of study data and reports in accordance with regulatory and quality requirements.
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• Perform other related duties as assigned.
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To qualify specifically for this role, you will have:

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• Master's degree or higher in a scientific discipline.
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• 13-15+ years of relevant experience in CRO, pharmaceutical, or academic research environments.
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• Demonstrated record of sustained scientific leadership, innovation, and delivery of complex, high‑visibility programs.
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• Expert understanding of bioanalytical science, GLP regulations, scientific risk management, and quality systems.
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• Proven ability to manage multiple high‑complexity programs simultaneously while meeting timelines and quality expectations.
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• Recognized expert in applicable laboratory techniques and bioanalytical methodologies.
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• Strategic scientific thinking with organizational‑level influence.
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• Strong leadership, mentoring, and decision‑making capabilities.
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• Exceptional communication skills with the ability to convey complex scientific concepts clearly to diverse audiences.
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• Commitment to advancing scientific excellence, client trust, and KCAS Bio's scientific reputation.
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(Please note this is a representative summary of responsibilities, not a comprehensive or exclusive list of the duties to be performed in any position. Employees must follow instructions and perform additional duties as requested.)

WHO YOU ARE

You will thrive at KCAS Bio if you enjoy a relational environment, are purpose- and values-driven, embrace constant development and supportive leadership, and enjoy being part of innovative work.

WHAT YOU'LL GET

Our benefits include, and extend beyond, the traditional package. At KCAS Bio, you will enjoy company sponsored events like food trucks, family days and spirit days. You will grow in your career with KCAS University. You will be able to connect with like-minded employees to further KCAS Bio's approach to key areas such as wellness, inclusion, and community outreach. You will engage as an owner in our stock ownership program. You will have access to the latest technology. And you will be able to invest in the community with paid time off to volunteer.

Learn more about the Benefits at KCAS Bio

WHO WE ARE

We are a fast-growing contract research organization (CRO) headquartered in Kansas City, pioneering the latest drug development in both human and animal health fields. Demand for our expertise is growing and so is our need for great people to work in nimble, empowered teams committed to one another's growth. At KCAS Bio, we advance both great science AND great people.

Learn more about what it is like to work at KCAS Bio

KCAS Bio is proud to be an Equal Opportunity Employer. Among other things, we provide equal employment opportunities without regard to race, color, religion, national origin, ancestry, marital status, veteran status, age, disability, pregnancy, genetic information, sex, sexual orientation, gender identity, or any other legally protected category; we recruit qualified candidates without regard to citizenship status based on internal processes that enable us to hire the right candidates consistent with the appropriate U.S. Immigration framework; and (3) we work with and provide reasonable accommodations to individuals with disabilities and for sincerely held religious beliefs, observances, and practices. Anyone who needs reasonable accommodation may send an email to kcasrecruiting@kcasbio.com or call 913-248-3000 (for TTY assistance call 711) and ask for Human Resources.

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