Job Title: RA III or Scientist I (AI/ML Assay Design)
Pay Rate: $60/hr.
Location: San Diego, CA 92121
Duration: Approved until 7/18/2027
Position Overview: We are seeking an innovative Bioinformatics Scientist with expertise in AI/ML to build next-generation, high-throughput primer design systems for our diagnostic platforms. In this role, you will combine molecular biology, machine learning, and data engineering to develop intelligent pipelines that translate experimental data into improved assay performance. You will build models that learn from large-scale PCR and sequencing datasets, enabling data-driven optimization of assay design. This role is ideal for someone excited about applying modern ML and AI techniquesincluding deep learning and emerging language model approachesto real-world diagnostic challenges. Key Responsibilities: Experimental Data Analysis
Develop scalable pipelines to process and analyze high-throughput PCR and NGS datasets
Transform raw experimental outputs into structured datasets for modeling
Engineer biologically meaningful features (e.g., sequence composition, thermodynamics, secondary structure)
Machine Learning Development
Design, train, and deploy models to predict primer efficiency, specificity, and robustness
Integrate sequence-derived features, thermodynamic calculations, and experimental outcomes
Build reproducible ML workflows that support end-to-end assay design automation
Model Iteration & Optimization
Continuously refine models using newly generated experimental data
Implement frameworks for iterative learning, model retraining, and benchmarking
AI-Driven Applications
Develop AI-powered tools to support primer design, assay optimization, and data interpretation
Apply LLM-based methods for sequence annotation, workflow automation, and design recommendations
Contribute to reusable internal platforms enabling AI-assisted assay development at scale
Required Qualifications:
Education:
Ph.D. (02 years), M.S. (24 years), or B.S. (35+ years) in Bioinformatics, Computational Biology, Data Science, Molecular Biology, or a related field
Bioinformatics:
Strong foundation in sequence analysis, primer design, and computational biology workflows
Programming & Data Analysis:
Proficiency in Python, with experience in statistical analysis and experimental data interpretation
Machine Learning:
Hands-on experience developing ML or deep learning models using frameworks such as PyTorch, TensorFlow, or scikit-learn
Preferred Qualifications:
Experience with sequence-based modeling or genomic data analysis
Experience developing or maintaining reproducible bioinformatics workflows (e.g., Nextflow, Bash)
Experience working in Linux command-line and shared server environments
Experience using Git (e.g., pull requests, code review, issue tracking)
Understanding of PCR chemistry and assay design principles
Technical Skills:
Programming: Python (required), R, Git
Bioinformatics Tools: Primer3, BLAST, Biopython
Data & Engineering: Pandas, NumPy, SciPy, pipeline development
AI/Automation: LLMs, workflow automation tools, AI-assisted development
Operating Systems: Linux command-line environments, Linux-based servers, shared computational infrastructure
Why This Role Is Exciting You will apply AI/ML to molecular biology to design better assays for womens health and infectious disease detection.
Numbers & Facts
Location
San Diego, CA
Industry
Staffing/Employment Agencies
Company Size
500 to 999 employees
Year Founded
1999
Website
https://www.csetalent.com/
About Company
Connexion is an award-winning professional staffing firm that strives to be the unrivaled staffing solution for job seekers by expertly connecting talent with opportunity. Over the last 20 years Connexion has built the most admired team of staffing experts in the industry. We give back, change lives and offer unconditional support to the candidates we represent.
Put Connexion's 20 years of experience to work for you! Our professionals have unrivaled relationships and contacts with the hiring managers, human resources team and decision makers at the most desirable companies to work for.
Don't let your resume get lost in an inbox, Connexion's recruiting team will advocate on your behalf to get you the job you want
Skills
Analysis Skillsunmatched
Artificial Intelligence (AI)unmatched
Assay Developmentunmatched
Assaysunmatched
Automationunmatched
Bash Scriptingunmatched
Benchmarkingunmatched
Bioinformaticsunmatched
Biologyunmatched
Chemistryunmatched
Code Reviewsunmatched
Command Lineunmatched
Data Analysisunmatched
Data Modelingunmatched
Data Scienceunmatched
Data Setsunmatched
Deep Learningunmatched
Genomicsunmatched
Gitunmatched
High Throughputunmatched
Infectious Diseasesunmatched
Linux Operating Systemunmatched
Machine Learningunmatched
Modeling Languagesunmatched
Molecular Biologyunmatched
Operating Systemsunmatched
Performance Managementunmatched
Polymerase Chain Reaction (PCR)unmatched
Predictive Modelingunmatched
Process Improvementunmatched
Python Programming/Scripting Languageunmatched
R Programming Languageunmatched
Scalable System Developmentunmatched
Thermodynamicsunmatched
Training Data Setsunmatched
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