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Skills
Analysis Skillsunmatched
Assaysunmatched
Biologyunmatched
Cell Culturesunmatched
Chemistryunmatched
College Level Facultyunmatched
Cross-Functionalunmatched
Disease Investigationunmatched
Drug Designunmatched
Experiment Designunmatched
Fundingunmatched
Fungiunmatched
Grant Writingunmatched
Identify Issuesunmatched
Infectious Diseasesunmatched
Molecular Biologyunmatched
Multitaskingunmatched
Mycologyunmatched
Pharmacokineticsunmatched
Pre-Clinical Developmentunmatched
Pre-Clinical Trialsunmatched
Problem Solving Skillsunmatched
Project/Program Managementunmatched
Regulationsunmatched
Regulatory Requirementsunmatched
Replication and Remote Mirroringunmatched
Small Moleculesunmatched
Team Playerunmatched
Virusesunmatched
Description
Antifungal Discovery and Screening:
Design, develop, and execute in vitro assays to identify and characterize small-molecule and biologic antifungal candidates against emerging viruses, including Cryptococcus neoformans, Candida auris, C. albicans, Coccidioides immitus, and Aspergillus fumigatus.
In Vivo Evaluation of Antifungals:
Conduct and oversee preclinical in vivo studies in relevant animal models to assess efficacy, pharmacokinetics, and safety of antifungal candidates.
Mechanistic mycology Studies:
Investigate fungal replication, pathogenesis, and host-fungi interactions to inform rational drug design and optimization of antifungal therapeutics.
Collaboration and Project Management:
Coordinate with multidisciplinary teams including medicinal chemists, structural biologists, and clinicians to advance antiviral projects from discovery to preclinical development.
Scientific Communication and Reporting:
Prepare manuscripts, grant reports, and presentations to disseminate research findings and support funding and regulatory requirements.
Knowledge, Skills and Abilities:
Strong knowledge of mycology, fungal replication mechanisms, and host-fungus interactions.
Skilled in designing and performing in vitro antifungal assays, cell culture techniques, and molecular biology methods.
Skilled in conducting and interpreting in vivo animal studies for infectious diseases, including efficacy and PK/PD evaluation.
Ability to analyze, interpret, and present complex scientific data clearly in written and oral formats.
Demonstrated skills in experimental design, troubleshooting, and independent problem-solving.
Ability to work collaboratively in multidisciplinary teams and manage multiple projects effectively.
Knowledge and familiarity with biosafety regulations and experience working in BSL-2/BSL-3 laboratory environments