Research Associate, Ad/Qc With Chromatography Focus

About Terrestrial Bio, Inc.

Terrestrial is transforming the delivery of next-generation therapies, starting with GLP-1.

Terrestrial's proprietary Tacterra microarray patch (MAP) and applicator platform consists of a patch resembling an adhesive bandage, which is applied with a preloaded applicator and removed after a few minutes. Once applied, each patch delivers bioactive tips into the skin, which dissolve quickly into the body, rapidly releasing their therapeutic payload. Designed for self-administration, the temperature-stable Tacterra platform enables precise, controlled delivery of a wide range of therapeutics without medical sharps or refrigeration.

Terrestrial has generated strong clinical and in-vivo proof of concept across multiple molecules. For more information, visit www.terrestrialbio.com.

Why this role

Our team is seeking a motivated and detail-oriented Research Associates with strong hands-on experience in chromatographic analysis to support in-process, release, and stability testing for the MAP program. In this role, you will perform routine cGMP QC testing using HPLC/UPLC methods (reverse-phase, SEC, IEX), Agilent systems, and additional supporting assays. You will also perform HPLC/UPLC method development and troubleshooting to support early-phase clinical QC.

As part of a growing QC department, you will work in a collaborative, fast-paced, and cross-functional environment

What you'll do

• Perform routine QC in-process, release, and stability testing using HPLC/UPLC methods including reverse-phase, SEC, and IEX

• Perform HPLC/UPLC method development and troubleshooting in collaboration with senior scientists to support the QC workflow

• Prepare samples, operate Agilent systems, verify system suitability, and ensure analyses meet method and specification requirements

• Execute complementary analytical assays such as UV-Vis, pH, surface tension, and mechanical tests

• Maintain complete, accurate documentation in compliance with cGMP, ALCOA+, and data integrity requirements

• Conduct routine instrument care (solvent flushes, column care, daily checks)

• Process and review chromatographic data in Agilent OpenLab CDS

• Support method qualification, validation, and transfer activities by executing protocols and recording observations

• Maintain calibration, maintenance, and service records for analytical instrumentation

• Write and maintain key technical documentation including SOPs, analytical protocols, technical reports, and audit-ready records; contribute to regulatory submissions

• Collaborate cross-functionally with QC, Analytical Development, Process Development, Manufacturing, and Regulatory teams to enable program success

Who you are

• Bachelor's degree in Chemistry, Biochemistry, Chemical Engineering, or related field with 1-3 years of experience; or a master's degree with relevant laboratory experience

• Hands-on experience operating HPLC/UPLC systems; Agilent systems and OpenLab CDS experience strongly preferred

• Practical experience with chromatographic techniques including reverse-phase, SEC, and IEX

• Experience supporting QC release or stability testing in a GMP-aligned/GLP environment

• Strong attention to detail and ability to follow SOPs precisely

• Excellent documentation practices and understanding of data integrity

• Strong organizational skills with the ability to manage multiple workflows and prioritize effectively in a fast-paced environment

• Excellent verbal and written communication skills and comfort working within interdisciplinary teams

Compensation: The anticipated base salary range for this position is $60,000 - $75,000. Actual compensation will be determined based on a variety of factors including experience, qualifications, and internal equity.

Onsite expectations: The majority of our roles at Terrestrial are onsite, which allows us to meet both business and team needs. Candidates applying must be willing to be onsite 4-5 days per week.

Location: Woburn, MA and our new, custom facility in Allston MA planned for Q4 of 2026.

At Terrestrial, we're bringing together exceptional talent to drive our product development forward. We value collaboration, curiosity, and a dynamic work environment. We aim to recruit, employ, train, compensate and promote regardless of race, religion, color, national origin, sex, gender identity or expression, sexual orientation, disability, age, or veteran status.