Research Associate - Biology - III

Onsite Position - Foster City
Job title: Research associate III
Will need to be available to come in on weekends as needed.

DESCRIPTION
We are seeking a highly motivated research associate to join our Inflammation in vivo
pharmacology team. The selected candidate will provide in vivo study support under
minimal supervision for evaluating Client inflammation therapeutics in pre-clinical models
and will be responsible for daily in vivo study support needs, including frequent off-shift and
weekend study support needs for our inflammation studies.
Hands-on experience with preclinical mouse models is required. The successful candidate
will be highly proficient in murine handling techniques including various dosing routes (IV, IP,
PO, subcutaneous), in-life and terminal blood collection, and handling of tissues during
necropsy and processing for ex vivo analysis. The day-to-day responsibilities will include
daily dosing, animal body weights, tissue collections, and assisting with various aspects of
study maintenance.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
Reviews and complies with all policies, guidelines and operating procedures pertaining to the animal
care and research program.
Assemble, set up, operate and maintain any necessary experimental equipment to conduct in-vivo
studies.
Conduct laboratory procedures in compliance with established protocols/plans and with regulatory
and laboratory requirements.
Document experimental data in technical notebooks or approved electronic files including procedures
performed, existing conditions, observed results and variation from expected data patterns.
Maintain technical knowledge and understanding in his/her assigned area of responsibility.
Able to perform the following techniques in rodents:
Handling and Restraint
PO, IV, SQ, IP techniques are a must
Blood collection in rodents such as, but not limited to, retroorbital, tail vein, submandibular,
cardiac.
Body weight and food consumption measurements and assessment of mouse body condition
Rodent euthanasia using CO2, anesthesia and/or approved physical methods.
Provide inhalation anesthesia induction, monitoring if needed
Performing clinical observations of animals to determine morbidity/mortality/ animal health
check and treatment as needed
Perform necropsy, including tissue and fluid collections
Support study set-up, take downs, ex-vivo assays
Basic laboratory techniques, including pipette handling and formulation handling (including dose
calculations)
Interact with personnel within the department to develop a network of resources to facilitate
completion of assignments.
Strong communication and interpersonal skills
Perform all other related duties as assigned.
QUALIFICATIONS:
From other JD for reference:
Education/Experience: B.S./B.A. degree in Biological Sciences or related field, or Associate s degree in
veterinary technology or equivalent college level program. Must have at least 2 years of previous
technical experience in a laboratory animal research setting, specifically PK/PD experience. OR High
School diploma/GED and four (4) years directly related work experience in laboratory animal husbandry
and technical skills as detailed above required
An equivalent combination of education and experience may be accepted as a satisfactory substitute
for the specific education and experience listed above.
Qualifications & prior experience:
" 5+ years of laboratory animal facility experience, preferably in industry and
demonstrated work experience with murine models of cancer, inflammation and/or
immunology.
" Proficiency with various mouse handling techniques including dosing (PO, IV, SQ, IP),
body weight measurements, in life and terminal blood collection, and collection and
handling of tissues during necropsy and processing for ex vivo analysis.
" Knowledge of and experience with USDA regulations, laboratory animal welfare
guidelines and AAALAC, International guidelines is a plus, but not required.
" Working knowledge of laboratory animal equipment and supplies, for a variety of
common laboratory animals and personal protective equipment requirements for
various bio-safety levels.
" Excellent organizational and communication skills, along with the ability to work
effectively in a multidisciplinary team environment is essential.
" Computer literacy with MSWord and MS Excel is required. PowerPoint and GraphPad
Prism experience is desired.
" Demonstrated ability to organize and plan studies and execute day to day
responsibilities with minimum supervision.
WORK ENVIRONMENT: While performing the duties of this job, the employee is exposed to laboratory
animals and caging of various species including mice, rats, and other rodents and is occasionally exposed
to wet and/or humid conditions, toxic or caustic chemicals, biohazard materials/agents.
COMMENTS:
Normally 40 hours per week. Will be required to work independently and regularly on weekends,
earlier or later than core hours, during inclement weather events and/or holidays to complete duties.
Maintains required attendance levels and adheres to work schedule in accordance with required staffing
levels in order to ensure that assigned duties are completed.