Assay Development & Bioinformatics
Position Summary
The Research Associate I supports cross-functional molecular diagnostics research projects through the execution of laboratory experiments, generation of high-quality data, and maintenance of laboratory operations. Working closely with Assay Development and Bioinformatics teams, this individual performs molecular biology workflows, supports high-throughput screening activities, organizes experimental data, and contributes to data-driven assay development efforts.
The position serves as a bridge between laboratory experimentation and computational analysis, ensuring the generation and organization of high-quality data to support assay design and optimization activities. This position is ideal for an early-career scientist interested in molecular diagnostics, assay development, laboratory automation, and data-centric research.
Key Responsibilities
Perform molecular biology and assay development experiments following established protocols and study plans.
Prepare reagents, controls, oligonucleotides, standards, and biological samples for assay development activities.
Execute PCR, qPCR, RT-PCR, and other nucleic acid-based workflows using laboratory instrumentation and automated systems.
Support high-throughput screening studies through plate preparation, sample processing, and operation of laboratory automation platforms.
Collect, organize, document, and summarize experimental data in laboratory notebooks and electronic data management systems.
Assist with data compilation, quality checks, and preparation of datasets and associated metadata for downstream analysis.
Communicate experimental results, observations, and technical issues to project team members and supervisors.
Operate, maintain, and troubleshoot laboratory equipment and instrumentation as needed.
Manage laboratory inventory and support routine laboratory operations.
Follow established SOPs, laboratory safety requirements, and quality standards.
Collaborate effectively with scientists and bioinformaticians to support project goals and timelines.
Qualifications
Required
B.S. or B.A. in Molecular Biology, Biology, Biochemistry, Biotechnology, Chemistry, Genetics, or a related life science discipline.
0-2 years of laboratory experience in academic research, biotechnology, diagnostics, or related fields.
Basic understanding of molecular biology techniques, including PCR and qPCR.
Proficiency with Microsoft Office applications, particularly Excel, Word and PPT.
Strong organizational skills and attention to detail.
Preferred
Experience with molecular diagnostic assays.
Experience with automated liquid handling systems or other laboratory automation platforms.
Familiarity with high-throughput screening workflows.
Exposure to biological data analysis, data visualization, or bioinformatics concepts.
Experience working in a regulated laboratory environment.
Intake Notes:
Role Overview
Job Title: Research Associate I
Department: Assay Development & Bioinformatics
Number of Openings: 2
Location: 10210 Genetic Center Dr., San Diego, CA 92121
Work Model: Onsite
Duration: 6 Months
Extension Possible: Yes
Conversion Possible: Yes
Target Start Date: ASAP
Business Need
Support AI/ML-assisted oligonucleotide design initiative.
Generate high-quality experimental data to support molecular assay development.
Partner closely with Assay Development and Bioinformatics teams.
Top Required Skills
Molecular biology techniques (PCR, qPCR, ddPCR, nucleic acid extraction)
Experimental troubleshooting and data interpretation
Collaboration within cross-functional scientific teams
Must-Have Qualifications
BS/BA in Molecular Biology, Biotechnology, Biochemistry, Genetics, or related life science field
Hands-on PCR/qPCR experience
Molecular biology laboratory experience
Experience analyzing and interpreting experimental data
Strong documentation and organizational skills
Statistical analysis using JMP or similar software
Preferred Qualifications
Molecular diagnostics experience
Laboratory automation/liquid handling systems
High-throughput screening experience
Python, R, JMP, or bioinformatics exposure
Oligonucleotide design experience
Candidate Knockouts
No qPCR experience
No molecular biology lab experience
Cannot explain troubleshooting examples
No data analysis/interpretation experience
Team & Environment
Small collaborative team (5-6 scientists and research associates)
Reports to Kati Hokynar
Works closely with Meghan Altman and Bioinformatics team members
Compensation
Approved Pay Rate: ***/hour