Research Associate (MG)

University of Pennsylvania

Philadelphia, PA

JOB DETAILS
LOCATION
Philadelphia, PA
POSTED
30+ days ago


The Department of Cell and Developmental Biology at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for a Research Associate position in the Academic Support Staff. This appointment will be initially for one (1) year and continuation during that time period and renewal are based on satisfactory performance and availability of funding (limited to three (3) years). Expertise is required in the specific area of Molecular biology and tissue culture expertise. Confocal microscopy and image analysis expertise. Protein expression and purification expertise. Experience in DNA Damage-Repair field. Experience working with others on collaborative research projects. Applicants must have a Ph.D. degree.



Responsibilities may include characterization of the determinants of 53BP1 self-assembly to form DNA repair condensates in cancer cells. Perform microscopy and FACS based studies to quantify the condensation of 53BP1 and mutants that display assembly defects in vitro. Perform functional studies of non-homologous end-joining and DNA damage resolution in 53BP1-/- cell lines. Use biochemical reconstitution of purified fragments of 53BP1 C-terminus to identify the minimal regions required for phase separation. Work with collaborators to perform initial characterization of chromatin state in damaged cells, and to characterize LLPS of BRCA1 in homology directed repair.



The successful applicant will have an opportunity to further develop critical research skills, including project management, supervising students and other lab staff, working on presentations and writing papers.



Candidate should have a minimum of 3-5 years postdoctoral experience



We seek candidates who embrace and reflect diversity in the broadest sense. The University of Pennsylvania is an EOE. Minorities/women/individuals with disabilities/protected veterans are encouraged to apply.






The University of Pennsylvania is an equal opportunity employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, religion, creed, national origin (including shared ancestry or ethnic characteristics), citizenship status, age, disability, veteran status or any class protected under applicable federal, state, or local law.

About the Company

U

University of Pennsylvania

Penn's beautiful urban campus provides easy access to a range of educational, cultural, and recreational activities. We offer excellent healthcare and tuition benefits for you and your family, as well as generous retirement benefits, professional development opportunities and flexible work options. Penn is a diverse, multicultural learning community at the cutting edge of research and information technology. Click here to read more about why we're a Best Employer. Not only does Penn offer a unique environment within the city of Philadelphia to work, we also provide a wide array of employee benefits. From a competitive retirement program and comprehensive health care options to health promotion and wellness services and tuition assistance, there's a wealth of opportunities and resources available to you at Penn.

Penn is frequently cited as an outstanding employer:

  • Recipient of the 2010 Terri Lynne Lokoff Child Care Foundation Corporate Leadership Award for commitment to supporting worklife balance programs.
  • Selected as a recipient of the 2010 Healthy Workplace Award by the Philadelphia Business Journal and presenting sponsor UnitedHealthcare
  • Recognized as a 2010 Top Workplace by The Philadelphia Inquirer/Daily News.
  • Recipient of the 2009 Vision Award for commitment to workforce diversity and economic inclusion.
  • Selected for Computerworld's 100 Best Places to Work in IT six years in a row!
  • Recognized by the Delaware Valley Association for the Education of Young Children as a 2006 Best Employer for Working Parents
  • Named a Best Place to Work in the November 2007 issue of Philadelphia Magazine.
  • Designated a Best Workplace for Commuters by the National Center for Transit Research
COMPANY SIZE
100 to 499 employees
INDUSTRY
Advertising and PR Services
FOUNDED
1990
WEBSITE
http://www.cmimedia.com/