Research Scientist I

JOB DESCRIPTION:
JOB TITLE: Research Scientist
LOCATION: Lexington, MA
DURATION: 6 mos/1 year

TOP SKILLS PER MGR:
Post-degree wet lab experience in industry, expertise in cellular and molecular biology is essential (cell culture, cell-based assay, qPCR),
Experience with in vivo methodologies,
strong oral and written communication skills

Key Responsibilities:

• Conduct siRNA drug candidate screening, hit identification, and lead optimization
• Apply cellular and molecular biology methodologies, e.g., mammalian cell culture; in vitro screening (e.g., transfection); cell-based assays; PCR
• Support in vivo drug candidate testing (e.g., mouse dosing; sample analysis)
• Innovate and advance research projects to further optimize the siRNA platform
• Generate high-quality technical documentation and communicate findings internally and externally

Qualifications:

• MS w/2 years experience or PhD w/1 year experience in cell or molecular biology (or a related field) - experience must be post-degree experience preferably in drug discovery and in an industry setting
• Expertise in cellular and molecular biology is essential (e.g., mammalian cell culture; cell-based assays; qPCR)
• Experience with RNA-seq, library preparation and immunoprecipitation-based workflow are desired
• Proficiency in animal handling, dosing, and necropsy is desired
• Demonstrated ability to execute and interpret experiments rigorously, deliver reliable results and drive projects aggressively towards defined goals
• A strong team player with a high energy and a passion for contributing to the discovery and development of Client therapeutics
• Strong oral and written communication skills with a proven ability to contribute effectively to group projects in a team-oriented environment
• Innovative and creative; takes initiative