Research Specialist, Spatial & Genome Technologies

Position Summary

The Research Specialist will play a key role in the operation and advancement of single-cell and spatial genomics services, supporting investigators throughout the research lifecycle, from experimental design and sample preparation to data generation and quality assessment. The successful candidate will possess a strong background in molecular biology and genomics, with experience in next-generation sequencing, single-cell genomics, spatial biology technologies or related fields. This position offers the opportunity to work with a diverse research community and contribute to the development and implementation of innovative genomic technologies that accelerate scientific discovery.

Duties & Responsibilities

Perform genomic profiling workflows, including bulk RNA sequencing, single-cell genomics, and single-nucleus genomics. Responsibilities include evaluation of RNA, cell, and nuclei quality and quantity, accurate counting of dissociated cells and nuclei, operation of the Chromium System, construction of single-cell libraries and conducting library quality assessments (QA) using automated electrophoresis systems. Conduct imaging-based spatial genomics workflows, including operation, maintenance, and troubleshooting of the Xenium System, preparation and processing of samples, execution of Xenium runs, and monitoring of data quality and project deliverables. Conduct sequencing-based spatial genomic workflows, including operation of the of the CytAssist platform, Visium library construction, and library (QA). Coordinate laboratory operations, including inventory management, creation of project records, preparation and organization of reagents and consumables, and coordination of materials for bulk RNAseq, single-cell, and spatial genomics projects. Oversee routine maintenance of laboratory equipment, ensuring compliance with established procedures and documentation standards. Collaborate with technical support teams to troubleshoot and resolve instrument issues and workflow failures. Collaborate and communicate effectively with laboratory staff to prioritize workloads, allocate resources, monitor project progress, and coordinate workflows to ensure projects are completed according to established timelines and quality standards. Train employees and student workers on laboratory protocols, benchwork techniques, and laboratory safety procedures. Perform other duties as assigned.Perform other related duties and participate in special projects as assigned.