Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
Responsible for maintaining laboratory equipment, organizing and preparing samples, conducting experiments, and recording and analyzing data.
Qualifications
Education
Bachelor's Degree Related Field of Study required
Can this role accept experience in lieu of a degree?
Yes
Licenses and Credentials
Experience
Prior laboratory experience, either through academic coursework, internships, or employment 1-2 years preferred
Knowledge, Skills and Abilities
- Strong theoretical and practical knowledge of laboratory techniques and procedures.
- Familiarity with common laboratory equipment and instruments used in research experiments.
- Proficiency in data collection, analysis, and scientific software tools.
- Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
- Strong problem-solving skills and the ability to troubleshoot technical issues.
- Excellent written and verbal communication skills to effectively convey experimental procedures, results, and challenges.
Additional Job Details (if applicable)
The Miller Laboratory at the Massachusetts General Hospital Center for Systems Biology is recruiting a full-time Research Technician.
The Miller Laboratory for Precision Therapeutics develops new chemical and nanotechnology-based approaches for spatially controlled cancer therapy. Our research combines organic synthesis, bioconjugate chemistry, drug delivery, molecular imaging, cancer biology, immunology, and quantitative tissue analysis to understand and engineer how therapeutics behave within tumors.
The successful candidate will collaborate with postdocs and faculty on projects involving radiation-activated chemistry, drug conjugates, and externally triggered therapeutic systems. Research may include the testing and purification of radiation-responsive linkers and prodrugs; development and synthesis of antibody, protein, polymer, or nanoparticle conjugates; investigation of radiation-mediated payload activation; and characterization of new compounds using cell culture assays, mouse tumor models, and microscopy.
Projects may also incorporate radiopharmaceuticals, ultrasound-responsive drug delivery, bioorthogonal chemistry, molecular imaging, and studies of the tumor immune microenvironment. Therapeutic distribution and response may be evaluated using preclinical tumor models, multiplex tissue imaging, flow cytometry, single-cell analysis, and spatial-omics techniques.
The technician will work within a multidisciplinary environment and collaborate with chemists, cancer biologists, immunologists, engineers, imaging scientists, radiation oncologists, and other physician-scientists across Massachusetts General Hospital and the broader Harvard research community.
Experience in one or more of the following areas is beneficial:
Antibody–drug, protein–drug, or polymer–drug conjugates.
Stimuli-responsive or activatable chemistry.
Nanoparticle formulation and physicochemical characterization.
Radiochemistry and radiopharmaceuticals.
Cancer biology, tumor models, or cancer immunology.
Molecular imaging and microscopy.
Ultrasound-responsive materials or drug-delivery systems.
Pharmacology, pharmacokinetics, or biodistribution.
Flow cytometry, multiplex tissue imaging, single-cell sequencing, or spatial omics.
Applicants are not expected to have experience in all of these areas. Candidates with strong chemistry and cancer biology backgrounds who are interested in expanding into imaging, immunology, and translational therapeutics are particularly encouraged to apply.
Remote Type
Work Location
Scheduled Weekly Hours
Employee Type
Work Shift
Pay Range
$21.00 - $29.01/Hourly
Grade
5
EEO Statement:
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
| Location | Boston, Massachusetts |
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