Duration: 12 months contract Shift: Standard business hours (approximately 8:00 AM – 5:00 PM)
Job Description:
We are seeking a highly skilled, hands-on Scientist to support Discovery Biomarkers within Cardiometabolic Disease and Obesity & Related research programs.
This contract role is ideal for an independent experimentalist who enjoys developing, executing, troubleshooting, and interpreting biomarker assays that inform program decisions.
The successful candidate will generate high-quality biomarker data from mouse, non-human primate, and human biological samples; collaborate closely with Discovery Biomarkers scientists and cross-functional teams; and clearly communicate results to support project strategy and decision-making.
The ideal candidate will have experience beyond simply running established laboratory protocols.
Candidates should be capable of understanding why an assay is being performed and how results impact research objectives, rather than simply executing predefined procedures.
The team is specifically interested in candidates who have:
Owned assay development activities
Participated in assay optimization
Conducted assay validation work
Troubleshot technical issues independently
Evaluated assay performance and reliability
Generated data used for program decisions
Key Responsibilities: Experimental Execution and Assay Support
Independently execute biomarker assays, including ELISA, MSD, flow cytometry, qPCR, ligand-binding assays, and other immunoassay platforms as appropriate.
Process and analyze mouse, non-human primate, and human biological samples in accordance with SOPs and EHSS expectations.
Develop, optimize, and troubleshoot biomarker assays to improve assay robustness, reproducibility, and fit-for-purpose performance.
Prepare reagents, standards, controls, and samples; perform calculations; and ensure accurate assay setup and execution.
Data Generation, Analysis, and Communication
Generate high-quality, well-documented datasets suitable for internal decision-making, project updates, and cross-functional discussions.
Perform preliminary data analysis, quality review, and visualization using tools such as GraphPad Prism, Excel, or similar software.
Interpret results in partnership with Discovery Biomarkers scientists and contribute scientific insights and recommendations.
Present data, experimental conclusions, and assay troubleshooting updates to CMD/OaR Discovery Biomarkers team.
Maintain accurate and timely electronic laboratory notebook records, including protocols, raw data, calculations, deviations, and conclusions.
Program and Team Support
Provide hands-on biomarker support across multiple discovery-stage CMD/OaR programs.
Collaborate with Discovery Biomarkers, Precision Medicine, and cross-functional project teams to align assay work with program priorities.
Manage parallel experiments and timelines while maintaining strong attention to detail, data integrity, and scientific rigor.
Qualifications:
PhD in Biology, Biochemistry, Immunology, Pharmacology, or a related scientific discipline; or BS/MS in a related discipline with 5+ years of relevant hands-on laboratory experience.
Demonstrated experience in assay development, assay execution, and assay troubleshooting in translational or discovery research settings.
Strong working knowledge of biomarker assay platforms such as ELISA, MSD, AlphaLISA, Luminex, ligand-binding assays, or related immunoassay technologies.
Experience handling in vivo and ex vivo translational biological samples, including mouse, non-human primate, and/or human samples.
Experience with common cell and molecular biology techniques such as western blotting, qPCR, RNA/DNA isolation, and cell culture.
Proficiency with scientific data analysis and visualization software, including GraphPad Prism, Excel, or comparable tools.
Familiarity with SOP-driven laboratory workflows, EHSS expectations, and good documentation practices.
Strong organizational skills, attention to detail, and ability to support multiple programs in parallel.
Clear scientific communication skills and a collaborative working style.
Cardiometabolic, metabolic disease, obesity, or related therapeutic area research experience preferred.
Experience contributing to project team discussions, data reviews, and biomarker strategy conversations preferred.
Basic Qualifications:
Doctorate degree OR
Masters degree and 2 years of experience OR
Bachelors degree and 4 years of experience
Top Must Have Skill Sets:
Hands-on execution, troubleshooting, and development of immunoassays, especially ELISA and MSD.
Experience processing and analyzing human biological samples; comfort working with animal blood and tissue samples is also important.
Ability to independently analyze, document, interpret, and communicate immunoassay data.
Day-to-day Responsibilities:
The contractor will independently perform bench-based biomarker assays, including immunoassays such as ELISA, MSD, and related assay platforms.
Day-to-day responsibilities will include preparing biological samples, reagents, standards, controls, and assay materials; supporting assay development, optimization, and troubleshooting; processing and analyzing mouse, non-human primate, and human biological samples; and performing raw data review, calculations, quality checks, and preliminary analysis of assay results.
The contractor will accurately and promptly document experimental procedures, raw data, calculations, observations, and results in electronic lab notebooks, and will summarize and communicate findings to Discovery Biomarkers scientists to support multiple discovery-stage programs in parallel.
About US Tech Solutions: US Tech Solutions is a global staff augmentation firm providing a wide range of talent on-demand and total workforce solutions. To know more about US Tech Solutions, please visit www.ustechsolutions.com.
"US Tech Solutions is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, colour, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran"
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