Scientist I Cell Therapy Editing Strategy and Analytics

Scientist I, Cell Therapy Editing Strategy and Analytics

About Astellas

Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com.

Are you driven to make a real difference in the lives of patients?

We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.

Purpose & Scope

The primary purpose of Scientist I, Cell Therapy Editing Strategy and Analytics is to provide scientific expertise from the bench to enhance gene editing capabilities for the Cell Therapy Editing Team at AIRM. This role will work cross-functionally as part of a team planning and executing Process Development activities and develop editing strategies and processes for cell therapies across Astellas Primary Focus indications. This is a laboratory-based role in a fast-paced environment with opportunities for bringing cutting edge technologies to ensure efficient operation and on-time delivery of edited cells to ensure program timelines.

Role and Responsibilities

• Design and execute complex and novel gene-editing of pluripotent stem cells to develop strategies compatible with controlled cell therapy manufacturing applications and generate representative clones for downstream teams
• Lead efforts to evaluate and improve new cutting-edge gene editing technologies, develop genome engineering designs and molecular and cellular assays for characterization of edited cells
• Perform data collection, analysis, troubleshooting and interpretation with a high degree of scientific rigor
• Demonstrates understanding of process development, proactively identifies challenges and proposes solutions to management in a timely manner.
• Work cross-functionally, including project teams, to contribute to internal milestone achievements and generation of key deliverables
• Communicate results in both oral and written formats by participating regularly in team meeting preparations and presentations, including cross-functional team meetings
• Support preparation and review of technical slide decks, reports, Standard Operating Procedures (SOPs)regulatory filings and tech transfer
• Ensure smooth day-to-day operations, including on the weekends
• Perform other duties as assigned or special projects as needed
• Stay up to date on literature and mentor junior members