Scientist I

Compass Consulting

San Diego, CA

JOB DETAILS
SKILLS
Assays, Biotech and Pharmaceutical, Cloning, DNA, Gene Therapy, Journalism, Laboratory Notebook, Medical Conditions, Medical Products, Medical Treatment, Molecular Biology, Nucleic Acid, Polymerase Chain Reaction (PCR), Real-time PCR (qPCR), Research & Development (R&D), Sales Pipeline, Wheel/Front-End Loader
LOCATION
San Diego, CA
POSTED
30+ days ago
Our client is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. They are among the world's leading biotech companies, with multiple products on the market and a promising development pipeline.

Position Summary:

The Scientist I will be a vital contributor to our non-viral cell and gene therapy delivery platform, primarily focused on R&D for innovative nucleic acid payload technologies. This role involves evaluating novel mRNA and DNA designs using a range of molecular biology techniques, including plasmid cloning, in vitro validation, and the production of in vitro-transcribed mRNA. To verify successful expression, the scientist will utilize assays such as Western blot, qRT-PCR, and luciferase reporter assays.

Responsibilities:
  • Design and clone expression vectors and IVT donor plasmids to support research initiatives.
  • Execute DNA and mRNA transfections in mouse and human cell lines.
  • Assess nucleic acid expression through molecular methods like qPCR, reporter assays and Western blotting.
  • Maintenance of detailed electronic laboratory notebooks (ELN) and preparation of summary slides

About the Company

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Compass Consulting