Scientist I T cell & Immune Modulation Biology

General Information

Job Advert Title: Scientist I, T cell & Immune Modulation Biology

Location: Tsukuba,Ibaraki

Division: Oncology Research

Employment Class: Permanent

Description

About Astellas

Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. HP:Learn more about Astellas

Are you driven to make a real difference in the lives of patients?

We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.

/ Purpose & Scope

This is a pharmacologist position developing antibody therapeutics, such as T cell engager, for treating cancer based on the deeper biological understanding of modulating T cell activation. The position holder will have responsibility of own pharmacology studies, drive pharmacological study and report to pharmacology lead and Research Lead in each project. The pharmacological study includes in vitro and in vivo preclinical study to evaluate anti-tumor activities and MOA analysis of drug candidates for IND submission.

/ Essential Job Responsibilities

1. Plan and conduct appropriate non-clinical pharmacological studies, including animal studies, necessary to advance oncology projects, such as target identification, selection of drug candidates, confirmation of MOA, estimation of human dose, and exploration of combination drugs, under the guidance of the manager and team leader

2. Work in a team-oriented laboratory environment under the guidance of the manager and team leader, within cross-functional research teams (product creation, pharmacokinetics, safety, CMC, etc.) and other internal/external collaborators/stakeholders

3. Prepare patent specifications for parts related to non-clinical pharmacology data for patent filing of drug candidates.

4. Provide leadership, mentorship, and scientific/technical guidance to junior staff as opportunities arise.

/ Specific Physical or Environmental Requirements

This position is based in Tsukuba Research Center and will require on-site work.

/ Qualifications

/ Required

PhD with 3+ years or MS with 5+ years of relevant experience in pharmacology research

Desire and ability to work in cross-functional, flexible and team-oriented environment

Well-balanced communication skills (active & passive) in own language and in English

/ Preferred

Proficient in-vivo skills

Experience in cancer biology or immunology ()

/ Application Documents

Resumes

/ Selection details

/ 1

※

CV screening Aptitude test /First interview Final interview

• Please be advised that there might be a change in the process.

/ Location

Tsukuba, Ibaraki

※JRTX)

/ Start Date

Will be decided according to the candidate's flexibility

/ Contract Duration

Not limited to specified period

/ Probation Period

No probation period in principle

/ Salary

1

250,000100,000

3

1Base salary: will be decided by the candidate's experience, skill and capability.

2When Discretionary Work System is applied: Discretionary work allowance will be paid.(50,000100,000yen, based on the Grade)

3When Flextime System is applied: Overtime allowance will be paid for time worked in excess of prescribed working hours.

/ Salary Raise

/ Bonus

/ Allowance

Discretionary work allowance, Housing allowance, Commutation allowance, etc.

/ Working Hours

8:3017:308:3015:45

8:3017:30MonThu8:3015:45Fri

Discretionary Work System

/ Holidays

251

Weekends(Sat and Sun), holidays, May 1st, summer vacation, New Year holidays

/ Vacation Leave

Annual paid leave, childcare leave system, nursing care leave system, etc.

/ Welfare

Employment Insurance, Industrial Accident Compensation Insurance, Welfare Pension Insurance, Health Insurance, Mutual Aid Association System, Company Housing System, Employee Shareholder Association System, Property Accumulation Savings System

/ Career web site

https://re-jp.astellas.com/jp/recruit/newgraduates/

For more information about Astellas, please visit our career web site.

"We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law."

What awaits you at Astellas?

• Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide.
• Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
• Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.
• A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.

Our Organizational Values and Behaviors

Values: Innovation, Integrity and Impact sit at the heart of what we do.

Behaviors: We come together as 'One Astellas', working with courage and a sense of urgency. We are outcome focused and consistently take accountability for our personal contribution.