Scientist I

Pyramid, Inc

Waltham, MA

Apply

JOB DETAILS

SALARY

$40–$49 Per Hour

JOB TYPE

Contractor

SKILLS

Analysis Skills, Analytical Chemistry, Analytical Method Development, Assays, Automation, Biochemistry, Biotech and Pharmaceutical, Chromatography, Communication Skills, DNA, Data Analysis, Defense Intelligence Agency (DIA), Employee Benefits, Experiment Design, Gene Therapy, Healthcare, Identify Issues, Liquid Chromatography-Mass Spectrometry (LC-MS), Mass Spectrometry, Microsoft PowerPoint, Proteomics, Regulatory Compliance, Team Player, Test Plan/Schedule, Testing

LOCATION

Waltham, MA

POSTED

6 days ago

Immediate need for a talented Scientist I. This is a 12 Months Contract opportunity with long-term potential and is located in Waltham, MA (Onsite). Please review the job description below and contact me ASAP if you are interested.Job ID:26-14552Pay Range: $40 - $49/hour. Employee benefits include, but are not limited to, health insurance (medical, dental, vision), 401(k) plan, and paid sick leave (depending on work location). Key Responsibilities: Perform characterization testing of gene therapy samples to determine and quantify host cell proteins using solid-phase enhanced sample preparation and LC-MS analytical techniques commonly used in proteomics (i.e. proteomic profiling using DDA or DIA, targeted quantitation using MRM or PRM). Assist in analytical method development and execute method qualification experiments to establish accuracy, precision, linearity and sensitivity of quantitative method. Assist in developing automated liquid handler platforms to increase sample throughput. Document all method development and testing activities/results accurately in compliance with internal and regulatory standards.Key Requirements and Technology Experience: Skills-MASS SPECTROMETR, automation liquid handler, Method development and troubleshooting Master’s degree in Analytical Chemistry, Biochemistry, or a related discipline with 2-4 years of relevant biotechnology or pharmaceutical industry experience, preferably performing impurity monitoring using LC-MS or proteome/HCP profiling or Doctorate degree with 1-3 years of relevant experience in proteomics. Effective planning, communication and collaboration skills Strong theoretical understanding of macromolecules (e.g., DNA, RNA, proteins) and their chemical properties. LC-MS systems: Thermo Orbitrap Exploris/Eclipse/Fusion Lumos/Astral; Sciex LCMS Triple Quad 6500. Software: Skyline, Proteome Discoverer, Byos, Spectronaut. Practical, hands-on troubleshooting and programming experience with automation equipment, such as Agilent Bravo LT, Hamilton, Andrew or KingFisher. Gene therapy experience with AAV or LNP is preferred HM Notes: 8-person team, working standard 9–5 hours with some schedule flexibility and no planned overtime. The scientist will support protein and LC-MS–based analyses, with a strong focus on mass spectrometry, chromatography, and biological sample preparation. Daily work includes end-to-end digest workflow execution, optimization experiments, operating nano-LC and mass spectrometry platforms, monitoring instruments, running impurity and enzyme kinetic assays, and utilizing a mix of manual and automated liquid handling systems. The role also requires data analysis, experiment design based on team feedback, and clear communication of results through summaries and PowerPoint presentations. Ideal candidates hold a Master’s degree in Analytical Chemistry, Biochemistry, or a related field with 2–4 years of relevant biotech or pharma experience (or a PhD with 1–3 years), particularly with LC-MS impurity monitoring or proteomics/HCP profiling, and have experience with software such as Discover, Skyline, or similar peptide mapping tools. The position starts ASAP (with potential extension after 12 months)Our client is a leading Healthcare Industry and we are currently interviewing to fill this and other similar contract positions. If you are interested in this position, please apply online for immediate consideration. Pyramid Consulting, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.By applying to our jobs you agree to receive calls, AI-generated calls, text messages, or emails from Pyramid Consulting, Inc. and its affiliates, and contracted partners. Frequency varies for text messages. Message and data rates may apply. Carriers are not liable for delayed or undelivered messages. You can reply STOP to cancel and HELP for help. You can access our privacy policy here.#Mor2J2W:CB3

About the Company

Pyramid, Inc

Resume Resources

Free Resume Templates Free Resume Builder