Job Description
Scientist - III (Senior)
Location: South San Francisco, CA
Pay Rate: $76.97/hr.
Duration: 6 Months
Job Description
- Execute and troubleshoot molecular interaction studies supporting antibody discovery, hit identification, lead optimization, and candidate selection.
- Generate and analyze binding affinity, kinetics, avidity, epitope binning, competition, and developability data for antibodies, bispecifics, and other biologics.
- Operate and optimize molecular interaction platforms including SPR, Carterra, Biacore, BLI, KinExA, and related technologies.
- Perform protein characterization and quantitative analysis of protein-protein interactions.
- Design assay plans, establish appropriate controls, and interpret complex interaction data to support discovery decisions.
- Optimize assay workflows for robustness, throughput, data quality, and turnaround time.
- Troubleshoot assay and instrument issues and support protocol, analysis template, and workflow development.
- Document experimental methods, results, data quality assessments, and conclusions in laboratory systems and technical reports.
- Support data analysis, visualization, and workflow improvements for molecular interaction studies.
Education
- Master's degree in Biophysics, Biochemistry, Chemistry, Molecular Biology, Protein Sciences, Biomedical Engineering, or related field with 5+ years of hands-on experience.
- PhD in a related field preferred with 3+ years of hands-on experience.
Required Skills
- Biomolecular interactions
- Protein characterization
- Protein-protein interaction analysis
- Surface Plasmon Resonance (SPR)
- Carterra
- Biacore
- Bio-Layer Interferometry (BLI)
- KinExA
- Binding affinity and kinetic analysis
- Antibody/protein interaction assays
- Molecular interaction data analysis
- Assay troubleshooting
- Quantitative data interpretation
Preferred Skills
- Therapeutic antibody discovery
- Bispecific antibody characterization
- Epitope binning
- Competition assays
- Cell binding characterization
- Receptor pharmacology
- Developability assessment
- Antibody engineering
- Fc biology
- Protein structure-function analysis
- Flow cytometry
- High-throughput screening
- Laboratory automation
- Python
- R
- Spotfire
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Numbers & Facts
| Location | South San Francisco, CA |
| Industry | Staffing/Employment Agencies |
| Company Size | 500 to 999 employees |
| Website | https://www.thefountaingroup.com/ |
About Company
The Fountain Group provides Contingent Labor, Statement-of-Work, and Contingent-to-Permanent resources to clients with an internal/external Contingent Labor Managed Service Program or Clients without a program. The Fountain Group is committed to the belief that we all share in the responsibility to conduct our businesses in a socially and environmentally responsible manner. We base this on the premise that a company is much more than the products it offers. The effect a company has on the environment, the people and the communities it serves reflects the company’s dedication to being not only a good business, but to being a good corporate citizen. The Fountain Group believes the key to servicing a client is to identify the client demand precisely. Therefore, The Fountain Group focused its efforts on building and developing a process, which can identify an exact match for our client’s needs. Our process utilizes modern technology combined with 30+ years of Talent Acquisition experience to deliver Precision resources. Financial strength is prominent among The Fountain Group’s corporate values. The future of our business will be built on the innovation, compassion, outstanding services and technology, but a solid financial foundation is required to carry us forward to meet our business goal and support our long term vision.
Skills
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