Job Description
Bill: $119.05
Pay: $85-79
Spread:467.6-762.3
Duration:1 year
Job Title: Scientist III
Location: Onsite - South San Francisco (Local candidates only)
Job Description:
The CAR-T Biology team in South San Francisco, part of the Immuno-Oncology Organization, is seeking a Scientist III to support the development of in vivo CAR-T platforms from concept through preclinical development. The candidate will work at the intersection of synthetic biology and immune modulation. The ideal candidate will bring deep expertise in CAR-T biology, T-cell functional assays, and therapeutic development. The role includes designing CAR constructs, executing advanced cell-based assays and collaborating with cross-functional teams to generate high-quality data that support pipeline programs.
Key Responsibilities:
Apply subject matter expertise in T cell and synthetic biology approaches toward the development of the next-generation in vivo CAR-T cell therapies, and the ability to translate evolving scientific and intellectual property insights into impactful therapeutic programs.
Independently establish, track, and deliver on project milestones and experimental timelines, ensuring alignment with program objectives and organizational priorities, while adapting to evolving scientific needs.
Design and execute in vitro assays to evaluate CAR-T biology, including assessment of cytotoxicity, T-cell effector function, and immune cell phenotyping.
Organize, analyze, and synthesize complex scientific data, and effectively communicate experimental strategies, results, and interpretations to internal and external stakeholders through clear and impactful presentations and scientific reports.
Maintain comprehensive and well-documented records in an Electronic Lab Notebook (ELN).
Qualifications:
BS, or equivalent education, with typically 7 or more years of experience; or MS, or equivalent education, with typically 5 or more years of experience; or PhD level with experience in CAR-T, genetic medicine, or immuno-oncology.
Demonstrated ability to independently design, perform, and interpret key experiments to address scientific questions. Proven capacity to quickly learn and apply new laboratory techniques. Able to manage multiple tasks efficiently while meeting deadlines. Strong skills in scientific writing and verbal communication.
Extensive experience in assay development for CAR-T candidate generation and assessment
Previous experience in chimeric antigen receptor (CAR) construct design, CAR-T production, and T cell function evaluation.
Deep expertise in primary T cell isolation, activation, transduction, T cell cytotoxicity, proliferation, cytokine profiling, multi-color flow cytometry, and immunological assays (e.g., ELISA, Luminex, cytotoxicity assays) is required.
Previous experience in leading preclinical cell therapy projects and mentoring scientists will be a plus
Experience in cell-based in vitro assay development and semi-automated liquid handling systems for high-throughput workflows is a plus.
Bussiness Unit:
R&D-Discovery (RDDI)
Cost Allocation:
6003|CC|RDI ODR LC (601802)
Pay: $85-79
Spread:467.6-762.3
Duration:1 year
Job Title: Scientist III
Location: Onsite - South San Francisco (Local candidates only)
Job Description:
The CAR-T Biology team in South San Francisco, part of the Immuno-Oncology Organization, is seeking a Scientist III to support the development of in vivo CAR-T platforms from concept through preclinical development. The candidate will work at the intersection of synthetic biology and immune modulation. The ideal candidate will bring deep expertise in CAR-T biology, T-cell functional assays, and therapeutic development. The role includes designing CAR constructs, executing advanced cell-based assays and collaborating with cross-functional teams to generate high-quality data that support pipeline programs.
Key Responsibilities:
Apply subject matter expertise in T cell and synthetic biology approaches toward the development of the next-generation in vivo CAR-T cell therapies, and the ability to translate evolving scientific and intellectual property insights into impactful therapeutic programs.
Independently establish, track, and deliver on project milestones and experimental timelines, ensuring alignment with program objectives and organizational priorities, while adapting to evolving scientific needs.
Design and execute in vitro assays to evaluate CAR-T biology, including assessment of cytotoxicity, T-cell effector function, and immune cell phenotyping.
Organize, analyze, and synthesize complex scientific data, and effectively communicate experimental strategies, results, and interpretations to internal and external stakeholders through clear and impactful presentations and scientific reports.
Maintain comprehensive and well-documented records in an Electronic Lab Notebook (ELN).
Qualifications:
BS, or equivalent education, with typically 7 or more years of experience; or MS, or equivalent education, with typically 5 or more years of experience; or PhD level with experience in CAR-T, genetic medicine, or immuno-oncology.
Demonstrated ability to independently design, perform, and interpret key experiments to address scientific questions. Proven capacity to quickly learn and apply new laboratory techniques. Able to manage multiple tasks efficiently while meeting deadlines. Strong skills in scientific writing and verbal communication.
Extensive experience in assay development for CAR-T candidate generation and assessment
Previous experience in chimeric antigen receptor (CAR) construct design, CAR-T production, and T cell function evaluation.
Deep expertise in primary T cell isolation, activation, transduction, T cell cytotoxicity, proliferation, cytokine profiling, multi-color flow cytometry, and immunological assays (e.g., ELISA, Luminex, cytotoxicity assays) is required.
Previous experience in leading preclinical cell therapy projects and mentoring scientists will be a plus
Experience in cell-based in vitro assay development and semi-automated liquid handling systems for high-throughput workflows is a plus.
Bussiness Unit:
R&D-Discovery (RDDI)
Cost Allocation:
6003|CC|RDI ODR LC (601802)
Numbers & Facts
| Location | South San Francisco, CA |
| Industry | Staffing/Employment Agencies |
| Salary | $79–$85 Per Hour |
| Company Size | 500 to 999 employees |
| Website | https://www.thefountaingroup.com/ |
About Company
The Fountain Group provides Contingent Labor, Statement-of-Work, and Contingent-to-Permanent resources to clients with an internal/external Contingent Labor Managed Service Program or Clients without a program. The Fountain Group is committed to the belief that we all share in the responsibility to conduct our businesses in a socially and environmentally responsible manner. We base this on the premise that a company is much more than the products it offers. The effect a company has on the environment, the people and the communities it serves reflects the company’s dedication to being not only a good business, but to being a good corporate citizen. The Fountain Group believes the key to servicing a client is to identify the client demand precisely. Therefore, The Fountain Group focused its efforts on building and developing a process, which can identify an exact match for our client’s needs. Our process utilizes modern technology combined with 30+ years of Talent Acquisition experience to deliver Precision resources. Financial strength is prominent among The Fountain Group’s corporate values. The future of our business will be built on the innovation, compassion, outstanding services and technology, but a solid financial foundation is required to carry us forward to meet our business goal and support our long term vision.