Scientist

Lancesoft

San Diego, CA

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JOB DETAILS

SALARY

$45

SKILLS

Analysis Software, Analytical Development, Antibodies, Assay Development, Chemistry, Communication Skills, Cross-Functional, Detail Oriented, Gene Therapy, Laboratory Notebook, Microscopy, Microsoft Excel, Nanotechnology, Nucleic Acid, Polymers, Presentation/Verbal Skills, Prism, Process Improvement, Small Molecules, Standard Operating Procedures (SOP), Writing Skills

LOCATION

San Diego, CA

POSTED

10 days ago

Working Model: Fully Onsite - 9360 Towne Centre Dr, San Diego, CA 92121
Working Days: Monday through Friday
Working Hours: 9 AM to 5: 30 PM PT
Interview Model: Two rounds (Virtual - 30 minutes each)

Job description

We seek an outstanding candidate to join the gRED Gene Therapy Nanotechnology team. The Scientist I will contribute to our cutting-edge delivery platform by designing, preparing, and characterizing ligand conjugates and targeted lipid nanoparticles. A critical component of this role is supporting targeted delivery systems through bioconjugation chemistry, including preparing protein conjugates and formulating targeted LNPs. Responsibilities include executing bioconjugations (e.G., antibodies, peptides) with small molecules or polymers;validating and purifying bioconjugates via LC-TOF and A KTA purification station;formulating non-targeted and targeted LNPs encapsulating nucleic acids using microfluidic or T-junction mixing technologies;performing surface bioconjugation for targeted LNPs;supporting analytical assay development (BLI, fluorescence microscopy, A KTA);evaluating ligand and particle stability under various conditions;maintaining electronic laboratory notebooks;and authoring SOPs.

Skills
Extensive hands-on experience in bioconjugation methodologies, process optimization, and bimolecular reaction kinetics. Prior expertise in Antibody-Drug Conjugate (Client) development is strongly preferred.
Proven experience with lipid nanoparticle formulation and LNP characterizations via RiboGreen, Dynamic Light Scattering (DLS), and Zeta potential measurement.
Proficiency in bioconjugation and formulating buffers is required.

Excellent attention to detail and ability to produce consistent results and effectively communicate with cross-functional teams.
Proficiency in MS Excel is required;prior experience with advanced analytical software (Prism, JMP) is desirable.
Excellent oral and written communication skills.

Education
MS with 2+ years or BS with 5+ years in pharmaceutical sciences, bioengineering, chemical engineering, chemistry, or a related scientific discipline (an equivalent combination of education and experience may be considered).

About the Company

Lancesoft

We are a $125 Million, NMSDC-certified Minority & Woman owned Workforce Solutions Company headquartered in the DC metro area with presence across US with global presence - Canada, Mexico, India, UK, Malaysia, Indonasia, Hongkong, Singapore, UAE. We are specialized in providing Workforce Solutions, SOW project delivery, Engineering Solutions, Creative Services. We currently support 100+ Fortune companies globally and across multiple industry segments. We are currently supporting several massive programs across industry segment nationally/globally (Intel, Ally, AMD, QUALCOMM, Morgan Stanley, Kraft/ Mondelez, MNP, Amdocs, Dell, SanDisk, Medtronic, Becton Dickinson, GE, Lockheed Martin, UTC, L-3 Communications, Caterpillar, BMW, Mercedes Benz, National Grid, Dominion, Energy Future Holdings, PSEG, 3M, Fidelity, Aetna, Humana, Johnson & Johnson, Pfizer, Merck etc).

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender, identity, national origin, disability, or protected veteran status.

COMPANY SIZE

2,000 to 2,499 employees

INDUSTRY

Staffing/Employment Agencies

FOUNDED

2000

WEBSITE

http://www.lancesoft.com/

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