Scientist/Senior Scientist, Antibody Engineering

The Position

We are seeking a highly motivated and skilled Molecular Biologist to join our dynamic research team in Discovery Chemistry,. The successful candidate will play a key role in antibody engineering to support platform development and drug delivery initiatives. This position requires extensive hands-on experience in phage display, antibody engineering, and antibody characterization, supported by a strong foundation in molecular biology.

Responsibilities

• Design and construct mutant phage libraries for antibody affinity maturation or humanization.
• Perform molecular cloning, mutagenesis, antibody gene assembly, and expression vector design.
• Express and purify recombinant antibodies using bacterial and mammalian expression systems.
• Perform binding, specific and in vitro functional assays.
• Collaborate with cross-functional project teams to advance lead antibodies through drug development stages.
• Maintain accurate documentation and present findings at internal meetings.

Requirements

• Ph.D. in Biology, Biochemistry, Molecular Biology, or a related field.
• Hands-on experience with phage display technology for antibody engineering.
• Proficiency in molecular cloning, PCR, and mutagenesis.
• Experience with antibody expression and purification using E. coli, HEK293, and CHO systems.
• Strong analytical and problem-solving skills, with the ability to troubleshoot experiments independently.
• Excellent record-keeping, communication, and collaboration skills.
• Proven ability to adapt to fast pace and evolving research priorities
• Track record of scientific productivity, including peer-reviewed publications, conference presentations, or patents
• Additional experience in molecular biology and/or antibody discovery is highly desirable

Preferred

• Industry or postdoc experience